Hsu began her career in experimental theatre and comedy. From 2013 to 2015, Hsu made regular appearances on the
MTV reality comedy series
Girl Code. She landed her first recurring television role as Joy Armstrong in the
Hulu series
The Path. Hsu was called in for the first table reading of
The SpongeBob Musical in 2012 to read for
Karen, the anthropomorphic computer. She would go on to play the character on stage in Chicago in 2016 before making her Broadway debut in 2017. Meanwhile, Hsu originated the main character of Christine Canigula in the first performance of
Be More Chill at the regional
Two River Theater in
Red Bank, New Jersey. She would reprise the role in its off-Broadway run at the
Pershing Square Signature Center in 2018 and Broadway run at the
Lyceum Theatre in 2019. For her performance, she received
Lucille Lortel and
Drama Desk Award nominations. In 2019, Hsu joined the recurring cast of the
Amazon Prime series
The Marvelous Mrs. Maisel for its third season as Mei Lin. She and the rest of the cast won the 2020
SAG Award for Best Ensemble in a Comedy Series. Hsu starred in the 2020 independent film
Asking for It. Her breakthrough role came in 2022 when Hsu co-starred as Joy Wang, the depressed daughter of
Michelle Yeoh's character, and as the nihilistic antagonist Jobu Tupaki in
A24's
absurdist comedy-drama film
Everything Everywhere All at Once. The film opened at the 2022
South by Southwest (SXSW) to acclaim, and Hsu's performance was lauded by critics and audiences. She received the
Independent Spirit Award for Best Breakthrough Performance and nominations for the
Critics' Choice Award, the
Screen Actors Guild Award, and the
Academy Award for Best Supporting Actress. In June 2023, she was invited to join
the Academy as an actor. Hsu guest starred in the "
Escape from Shit Mountain" episode of the first season of
Peacock series
Poker Face, which was released in 2023. Later that year, Hsu starred in
Adele Lim's film
Joy Ride. She also appeared in an episode of the
Disney+ series
American Born Chinese, reuniting with fellow
Everything Everywhere All at Once costars Yeoh,
Ke Huy Quan, and
James Hong. ==Personal life==