Dubois made her professional debut at
Motorpoint Arena Cardiff in
Cardiff, defeating Vaida Masiokaite on points over six rounds. In her eighth pro-fight, she defeated Magali Rodriguez by unanimous decision to claim the
IBO lightweight title at
York Hall in London on 30 September 2023. Dubois made a successful first defense of her title with a unanimous decision win over Miranda Reyes at
Wembley Arena in London on 3 February 2024. In July 2024, it was announced Dubois had signed a long-term promotional deal with
Boxxer and would fight
Maira Moneo for the interim
WBC female lightweight world title at
Oakwell Stadium in
Barnsley on 3 August that year. She won by unanimous decision with the ringside judges scoring the fight 100–90, 100–89 and 99–90. On 11 December 2024, Dubois was upgraded to full WBC female lightweight champion after
Katie Taylor vacated the title. Dubois defended her titles against
Jessica Camara at
Park Community Arena in
Sheffield on 11 January 2025. The fight ended in a technical draw at the start of round three on the orders of the ringside doctor after Camara suffered a cut to her left eye caused by an accidental clash of heads. Having vacated the IBO title, she retained her WBC championship thanks to a majority decision win over Bo Mi Re Shin at the
Royal Albert Hall in London on 7 March 2025. Two judges scorecards read 98–92 and 98–93 in her favour, while the third had the fight as a 95–95 draw. On 9 December 2025, it was announced that Dubois had signed with
Most Valuable Promotions and would defend her title against Camilla Panatta at
Kaseya Center in
Miami, Florida, USA, as part of the undercard of the
Jake Paul vs. Anthony Joshua fight on 19 December. She knocked Panatta to the canvas in the sixth round and went on to win the fight by unanimous decision. She won by unanimous decision. ==Achievements==