The university was established as the
Tennessee Agricultural & Industrial State Normal School for Negroes in 1912. Its dedication was held on January 16, 1913. Significant expansion occurred during the presidency of
Walter S. Davis between 1943 and 1968. The postwar period resulted in the construction of "70 percent of the school's facilities" and the establishment of the graduate school and four other schools. In 1968, the college officially changed its name to Tennessee State University. In 1979, the
University of Tennessee at Nashville merged into Tennessee State due to a court mandate. In 2022, Tennessee State University was awarded $250 million from the
state legislature. The funds were intended to upgrade facilities and academic programs on campus. At the time of the award, the $250 million investment was the largest single investment into a historically black institution in the history of the country. In 2023, Tennessee State's most well known graduate,
Oprah Winfrey, served as the official commencement speaker for the first time. On March 28, 2024, Tennessee Governor
Bill Lee signed legislation that removed all of the school's board of trustees and replaced them with new members, subject to legislative confirmation. Characterizing the school as a “remarkable institution” he said, “I’m pleased to appoint these highly qualified individuals who will work alongside administrators and students to further secure TSU’s place as a leading institution.” State legislation authorizing the governor to vacate the board of trustees was prompted by the numerous instances of financial and procedural mismanagement uncovered in recent school audits. Representative
Ryan Williams specifically noted that the $250 million appropriation made by the legislature in 2022 was “completely blown through” and not used for infrastructure improvements as intended. Tennessee State University is divided into 10 schools and colleges and has seen steady growth since its inception. It remains the only public university in Nashville. Its health science program is the largest in the state and one of the largest in the nation. ==Campus==