The route between Cleveland and the eastern end of the Ocoee Scenic Byway follows the route of the Old Copper Road, a wagon trail dating back to the 1830s used for transporting copper from the mines in the
Copper Basin to Cleveland and Chattanooga. The route originally continued westward from downtown Cleveland, crossing the Tennessee River at a ferry in Hamilton County, through
Soddy-Daisy and across the
Cumberland Plateau, and joined where the concurrency splits from US 41 (now part of Interstate 24) near Pelham. This designation was removed in 1940 after the
Chickamauga Dam went into operation, flooding much of the original route, and the route was moved to its present concurrency with US 11 and 41. Much of this original route no longer exists even as county maintained road. The
Tennessee Department of Transportation (TDOT) has plans to restore this route with a new four lane highway and
toll bridge across the Tennessee River, providing Clevelanders with a more convenient access to
Nashville. The Ocoee Scenic Byway was the first National Forest Scenic Byway in the nation, designated on July 22, 1988 by the
United States Forest Service (USFS). In 1986, TDOT began preparations to widen the entire segment of US 64 between Memphis and Pelham to four lanes, a distance of about , or about 70% of the length of the route in Tennessee. The final project, in Hardin County, was completed in the fall of 2017. In November 2009, a massive rock slide closed the Ocoee Scenic Byway for several months. This was reportedly the largest rockslide in the area's history. ==Route description==