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Tetrapyrrole

Tetrapyrroles are a class of chemical compounds that contain four pyrrole or pyrrole-like rings. The pyrrole/pyrrole derivatives are linked by, in either a linear or a cyclic fashion. Pyrroles are a five-atom ring with four carbon atoms and one nitrogen atom. Tetrapyrroles are common cofactors in biochemistry and their biosynthesis and degradation feature prominently in the chemistry of life.

Structure
Linear tetrapyrroles (called bilanes) include: • Heme breakdown products (e.g., bilirubin, biliverdin) • Phycobilins (found in cyanobacteria) • Luciferins as found in dinoflagellates and euphausiid shrimps (krill) File:Bilirubin ZZ.png|Bilirubin File:Biliverdin3.svg|Biliverdin File:Phycoerythrobilin.svg|Phycoerythrobilin File:Luciferin dinoflagellate.svg|Dinoflagellate (R=H) and krill (R=OH) luciferin File:Uroporphyrinogen III skeletal.svg|uroporphyrinogen III, an authentic tetrapyrrole Cyclic tetrapyrroles having four one-carbon bridges include: • Porphin, the simplest tetrapyrrole • Porphyrins, including heme, the core of hemoglobin • Chlorins, including those at the core of chlorophyll. Cyclic tetrapyrroles having three one-carbon bridges and one direct bond between the pyrroles include: • Corrins, including the cores of cobalamins, when complexed with a cobalt ion. File:Heme.svg|Heme group of hemoglobin with a porphin macrocycle. File:C-3 position Chlorophyll a.svg|The chlorin section of the chlorophyll a molecule. The green box shows a group that varies between chlorophyll types. File:Cobalamin.svg|Cobalamin structure includes a corrin macrocycle. The tetrapyrrole portions of the molecules typically act as chromophores because of a high degree of conjugation in them. Therefore, these compounds are commonly colored. ==References==
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