•
He-Man/Prince Adam (voiced by
Doug Parker as Adam,
Garry Chalk as He-Man) – The protector of Eternia who is summoned to Primus to help fight the Evil Mutants. When on Primus, Adam turns into He-Man by quoting "By the power of Eternia, I have the Power." •
Skeletor (voiced by
Campbell Lane) – The archenemy of He-Man. Upon being accidentally brought to Primus, Skeletor forms an alliance with the Evil Mutants of Denebria by telling Flogg that he will help him take over Primus in exchange for Flogg helping him destroy He-Man. By the end of the series, Skeletor and Crita are last seen in a shuttle pod disappearing into the depths of space.
Galactic Guardians •
Flipshot (voiced by
Scott McNeil) – A space pilot from the cloud city of Levitan. He is also known as
Icarius in the toyline. •
Hydron (voiced by
Don Brown) – An undersea commander and the captain of the Starship Eternia who comes from Primus' underwater city of Serus. •
Kayo (voiced by
Don Brown) – A space warrior and space pilot from Onnor in the Terra region of Primus. He is also known as
Tatarus in the toyline. •
Nocturna (voiced by
Alvin Sanders) – A martial artist and master of stealth from the Eastern continent of Mida. He was mostly seen as a background character. •
Vizar (voiced by
Don Brown) – A warrior with strong powers of sight who comes from the ancient city of Olympic in the Opal region of Primus. •
Tuskador (voiced by
Alvin Sanders) – An intergalactic
merchant warrior from the Polarides star system with tusks on his
elephant-like armor that he uses to catch enemies with. He is also called
Insyzor in the toyline. •
Artilla (voiced by
Garry Chalk) – A
cyborg weapons expert. He is also called
Weaponstronic in the toyline. •
Spinwit (voiced by
Ted Cole) – A warrior from the planet Zil who can create tornadoes by spinning. He is also called
Tornado in the toyline. •
Sagitar (voiced by
Campbell Lane) – A Horse Lord and former slave in the Denebrian Mines and arch-enemy of Staghorn who comes from the planet Equinos. His kind can turn from
centaur-like beings to four-armed humanoids. He is also called
Tharkus in the toyline.
Evil Mutants of Denebria •
Flogg (voiced by
Alvin Sanders) •
Hoove (voiced by
Doug Parker) – A mutant with powerful kicks who is often paired with Karatti. •
Lizorr – A reptilian mutant from the desert of Gorn. He was mostly seen as a background character. In "Glastnost Schmaznost," Lizorr was shown to extend his tongue as seen when he wraps it around He-Man's arm. •
Quakke (voiced by
Don Brown) – A super-strong mutant warrior who can shake the ground by hitting it with his Grabatron Meteormace. He is also called
Earthquake in the toyline. •
Staghorn (voiced by
Ted Cole) – A scheming Evil Mutant
tracker that wears a helmet with large metal pikes protruding from it which he uses in battle to pick up his enemies and throw them around. He comes from the Regula Mountains in the deepest, darkest part of the frozen Fog Zone on Denebria. Staghorn is the archenemy of Sagitar. •
Butthead (voiced by
Scott McNeil) – A mutant who attacks his enemies by ramming them with his head. Known as
"B.H." on the cartoon. •
Crita (voiced by
Venus Terzo) – A crafty female Mutant and later Queen of the Gleanons. She is an attractive and ruthless Evil Mutant who works on the Mutant Mothership and is attracted to Skeletor. By the end of the series, He-Man traps Skeletor and Crita in a shuttle pod and banishes them into space. •
Tech Mutants – Two unnamed Mutants that work as scientists for Flogg. •
Mutant Troopers – The generic foot soldiers of the Evil Mutants. Some of them are shock troopers while others pilot their shuttle pods for air attacks.
Other characters •
Master Sebrian (voiced by
Anthony Holland) – The wisest and most knowledgeable man on the planet Primus and the only one who Adam reveals his secret identity to. To help keep Adam's secret, Master Sebrian allows Adam to pass off as his merchant nephew from Levitan. He also has a knowledge of magical spells. •
Mara (voiced by
Venus Terzo) – An assistant of Master Sebrian, ambassador of Primus, and eventually the leader of the Galactimytes. She is shown to have good fighting skills when she goes up against Crita. •
The Scientists of Primus – The Scientists of Primus are the four greatest scientists of the planet whom, while intelligent, often provide the comedy relief in the show. •
Alcon (voiced by
Garry Chalk) – Member of the Scientists of Primus. He is very flamboyant and full of himself. Behind the massive ego of Alcon is a brilliant mind that he used to save Primus on more than one occasion. •
Gepple (voiced by
Don Brown) – Member of the Scientists of Primus. Even though most of the time he's just as bickering and cowardly as his partners, there are times that Gepple is more level-headed than the others. Gepple is also the inventor of a glue called "Gepple Goo" which has come in handy in most episodes. •
Krex (voiced by
Scott McNeil) – Member of the Scientists of Primus and the smartest of the group. He has a terrible memory of things. •
Meldoc (voiced by
Doug Parker) – Member of the Scientists of Primus. He has a tendency of falling asleep where he dreams of his next invention causing the other three scientists to give him a rude awakening. •
Drissi (voiced by Tracy Eisner) – Tends to the animals on planet Primus in its Oasis and occasionally lends a hand to the Galactic Guardians with her piloting skills and telepathic control over creatures. •
Caz (voiced by
Mark Hildreth) – A young boy with a thirst for adventure. It is hinted that he may be the heir to the rightful rulers of Primus. •
Gleep (voiced by
Ted Cole) – A robot that is often seen working for Master Sebrian. •
U-R – A robot who assists the Scientists of Primus and doesn't like being bossed around. •
Werban (voiced by
Don Brown) – The secretary of the Inner Council who cares for their needs. He has been shown to be jealous of Master Sebrian and misguided at times. •
Meliac – A
cyclops-like trader from Gorn City, Denebria that befriends He-Man. He later becomes the sheriff of Gorn City. •
Grot – A hippopotamus-like creature who handles Primus' gardens where he grows the food for the planet. He cares deeply for his garden. •
Priman Troopers – The foot soldiers of Primus. •
Korac – The former mayor of Gorn City who often does business with Skeletor. •
Mytes – The Mytes are a short race of peaceful aliens from the planet Nekron. •
President Pell (voiced by
Garry Chalk) – The wise and compassionate leader of the Mytes. •
Vice President Etor (voiced by
Ted Cole) – The second-in-command to President Pell who is also the best star pilot in the Myte Fleet. •
Ambassador Bimo – The Mytes ambassador to Primus. •
Gleanons – The Gleanons are a race of hostile aliens from the planet Nekron who are often in league with Crita. •
General Nifel (voiced by
Michael Donovan) – The leader of the Gleanons. •
Sgt. Krone (voiced by
Garry Chalk) – General Nifel's second-in-command. •
Private Dobson – The Gleanon's computer programmer. ==Episodes==