The pre-empire Tibetan people's accumulative knowledge of their local plants and their various usages for benefiting people's health were collected by
Tonpa Shenrab Miwoche (སྟོན་པོ་གཤེན་རབ་མི་བོ་ཆེ།), and passed down to one of his sons. Later,
Yuthok Yontan Gonpo the Elder compiled these practices and authored the
Gyud Shi or the
Four Tantras. While the
Ayurvedic Astāngahrdayasamhitā or the
Heart of Medicine Compendium attributed to
Vagbhata was translated into Tibetan by
Rinchen Zangpo (རིན་ཆེན་བཟང་པོ།) (957–1055), Ayurvedic practices had already been adopted in the 8th century by the Tibetan medical Council. Tibet had also absorbed the early Indian
Abhidharma literature, for example the 5th century
Abhidharmakosasabhasyam by
Vasubandhu, which expounds upon medical topics, such as fetal development. A wide range of Indian Vajrayana tantras, containing practices based on medical anatomy, had likewise been adopted by Tibet. In the 12th century,
Yuthok Yontan Gonpo the Younger (གཡུ་ཐོག་ཡོན་ཏན་མགོན་པོ།) visited India six times before editing the
Gyud Shi, or
Four Tantras, into its 156 chapters that are still in current use. The
5th Dalai Lama (ཏཱ་ལའི་བླ་མ་སྐུ་ཕྲེང་ལྔ་བ།) commissioned
Kalon Sangye Gyatso (སྡེ་སྲིད་སངས་རྒྱས་རྒྱ་མཚོ།) to establish the
Chagpori College of Medicine in 1696. Chagpori taught Gyamtso's
Blue Beryl as well as the
Four Tantras in a model that spread throughout Tibet along with the oral tradition. In the 1850s, the Russian capital at
Saint Petersburg opened a clinic of Tibetan medicine and a specialized school of Tibetan medicine. By 1898, a part of the Tibetan medical masterpiece the
Four Tantras or the
Four Medical Classics, was translated into the Russian language. In Poland, Tibetan medicine was practiced in the 1920s, and two presidents,
Stanisław Wojciechowski and
Ignacy Mościcki were both treated with Tibetan medicine. In 1969, the PADMA AG based in Zurich, Switzerland, was the first Western pharmaceutical company to specialize in the production and sale of Tibetan medicine. In September 1959, the Tibetan People's Government merged the
Men-tsee-khang (སྨན་རྩིས་ཁང་) and Chagpori College of Medicine and established the Lhasa Tibetan Hospital on this basis. In September 1961, at the congress of Tibetan doctors in Lhasa area, Chingpo Lobu was appointed as the director of Lhasa Tibetan Hospital. On September 1, 1980, the Chinese government of the Tibet Autonomous Region expanded Lhasa Tibetan Hospital to become
Tibetan Hospital of Tibet Autonomous Region (西藏自治区藏医院), laying a solid foundation for the vigorous development of Tibetan medicine. In 1999, Tibet Nordicam Pharmaceuticals Co., Ltd. became the first high-tech pharmaceutical listed enterprise of the Tibet Autonomous Region. In 2006, a medical group from the Tibet Autonomous Region was established in Lhasa, and by 2023 the Tibetan Hospital of Tibet Autonomous Region was renamed as the National Center for Traditional Chinese Medicine, "incorporating indigenous remedies" but removing references to Tibetan medicine and to Tibet. ==Four Tantras==