1982 Chicago Tylenol murders On September 29, 1982, a "Tylenol scare" began when the first of seven individuals died in the
Chicago metropolitan area after ingesting Extra Strength Tylenol that had been deliberately contaminated with
cyanide. Within a week, the company pulled 31million bottles of tablets back from retailers, making it one of the first major
product recalls in American history. As a result of the crisis, all Tylenol
capsules were discontinued, as were capsules of other brands. Calle & Company conceived the world's first
tamper-resistant gelatin-enrobed capsule called "Tylenol Gelcaps",) and a reward offered by
Johnson & Johnson remained unclaimed as of 2023. Before the poisonings, Tylenol brands held around 35% of the US market for acetaminophen and in the immediate aftermath, fell to 8%. Within a year sales had rebounded to the prior levels. These events led to the widespread use of tamper resistance packaging of drugs by drug companies, to the 1982 passage of a US federal law making
tampering a crime, and to legislation in 1989 requiring
tamper-proof packaging.
2010 Tylenol recalls In January 2010, a voluntary recall of several hundred batches of popular medicines was announced, including
Benadryl,
Motrin,
Rolaids, Simply Sleep, St. Joseph Aspirin, and Tylenol. The recall was due to complaints of a musty smell suspected to be due to contamination of the packaging with the chemical
2,4,6-tribromoanisole. The full health effects of 2,4,6-tribromoanisole are not known but no serious events have been documented in medical literature. The recall came 20 months after McNeil first began receiving and investigating consumer complaints about moldy-smelling bottles of Tylenol Arthritis Relief caplets, according to the US
Food and Drug Administration. The recall included 53 million bottles of over-the-counter products, involving lots in the Americas, the United Arab Emirates, and Fiji.
Children's Tylenol In April 2010,
another recall was issued for 40 products including liquid infant and children's pain relievers Tylenol and
Motrin, and allergy medications
Zyrtec and
Benadryl. In May 2010, the FDA confirmed that the bacterium found at the Johnson & Johnson plant that made the recalled Children's Tylenol was
Burkholderia cepacia, a bacterium often resistant to common antibiotics. The bacteria were found on the outside of certain product-containing drums, but not in the finished product. The US
Centers for Disease Control and Prevention stated that
Burkholderia cepacia is not likely to cause health problems for those with healthy immune systems. Those with weaker ones and those with chronic lung diseases, such as
cystic fibrosis, could be more susceptible to infection. ==Advertising==