Born into a farming family in Tuttwil, a small village now part of
Wängi, in the Swiss canton of
Thurgau, Hoepli began his career at 14 as an apprentice at the Schabelitz bookstore in
Zurich. He later moved to Germany, then to Poland, and eventually to
Trieste. While on a trip to Cairo, he was appointed by the
Khedive of Egypt
Isma'il Pasha to reorganize a library collection. In 1870, Hoepli purchased a small bookstore in
Milan, near the
Duomo, and moved to the city. His bookstore quickly became a cultural hub for Milan's educated bourgeoisie, offering rare antique books and scientific and technical texts in multiple European languages. Hoepli died in Milan after sixty-four years of publishing activity. In 1958, the bookstore, then managed by his nephew Carlo, relocated to
Via Hoepli, the street posthumously named in his honor. An asteroid,
8111 Hoepli, was also named after him. ==Publishing activity==