Sexual Health Educators and Public Health Agencies recommend a range of safe-sex practices. Many of these practices can reduce (but not eliminate) risk of transmitting or acquiring STIs.
Phone sex/cybersex/sexting Sexual activities, such as
phone sex,
cybersex, and
sexting, that do not include direct contact with the skin or
bodily fluids of sexual partners, carry no STI risks and, thus, are forms of safe sex.
Non-penetrative sex of
manual stimulation of the penis,
Johann Nepomuk Geiger, 1840A range of sex acts called
non-penetrative sex or
outercourse can significantly reduce STI risks. Non-penetrative sex includes practices such as
kissing, mutual masturbation,
circle jerks, manual sex, rubbing, or stroking. According to the Health Department of Western Australia, this sexual practice may prevent pregnancy and most STIs. However, non-penetrative sex may not protect against infections that can be transmitted via skin-to-skin contact, such as
herpes and
human papilloma virus. Mutual masturbation and manual sex carry some STI risk, especially if there is skin contact or shared bodily fluids with sexual partners; the risks are significantly lower than other sexual activities. • External
condoms can be used to cover the penis, hands, fingers, or other body parts during sexual penetration or
oral sex. •
Medical gloves and
finger cots made out of latex, vinyl,
nitrile, or polyurethane can cover hands or fingers during
manual sex or may be used as a makeshift dental dam during oral sex. • Condoms, dental dams, and gloves can also be used to cover
sex toys such as
dildos during sexual stimulation or penetration. Personal lubricants can also be water-based or silicone-based. While the use of external condoms can reduce STI risks during sexual activity, they are not 100% effective. One study has suggested condoms might reduce HIV transmission by 85% to 95%; effectiveness beyond 95% was deemed unlikely because of slippage, breakage, and incorrect use. It also said, "In practice, inconsistent use may reduce the overall effectiveness of condoms to as low as 60–70%". As of 2018, the most widely approved form of
PrEP combines two drugs (tenofovir and emtricitabine) in one pill. That drug combination is sold under the brand name
Truvada by Gilead Sciences. It is also sold in generic formulations worldwide. Other drugs and modalities are being studied for use as PrEP. Different countries have approved different protocols for using the tenofovir/emtricitabine-combination drug as
PrEP. That two-drug combination has been shown to prevent HIV infection in different populations when taken daily, intermittently, and on demand. Numerous studies have found the tenofovir/emtricitabine combination to be over 90% effective at preventing HIV transmission between sexual partners. AVAC has developed a tool to track trends in PrEP uptake across the globe. In 2025, Gilead announced approval for a PrEP shot that is effective for 6 months at a time, increasing the likelihood of adequate suppression.
Treatment as prevention Treatment as Prevention (often abbreviated as
TasP) is the practice of testing for and treating HIV infection as a way to prevent further spread of the virus. Those who know their HIV-positive status can use safe-sex practices to protect themselves and their partners (such as using condoms, sero-sorting partners, or choosing less-risky sexual activities). And, because HIV-positive people with durably suppressed or undetectable amounts of HIV in their blood
cannot transmit HIV to sexual partners, sexual activity with HIV-positive partners on effective treatment is a form of safe sex (to prevent HIV infection). This fact has given rise to the concept of "U=U" ("
Undetectable = Untransmittable").
Other forms of safe sex Other methods proven effective at reducing STI risks during sexual activity are: •
Immunization against certain sexually transmitted viruses. The most common vaccines protect against
hepatitis B and
human papilloma virus (HPV), which can cause
cervical cancer,
penile cancer,
oral cancer, and
genital warts. Immunization before initiation of sexual activity increases the effectiveness of these vaccines. HPV vaccines are recommended for all teen girls and women, as well as teen boys and men, through age 26 and 21, respectively. • Limiting the number of sexual partners, particularly
casual sexual partners, or restricting sexual activity to those who know and share their STI status, can also reduce STI risks.
Monamory and
Polyamory are safe when all partners are non-infected. However, several monogamous people have been infected with sexually transmitted infections by partners who engage in
infidelity or use injection drugs. The same risks apply to polyamorous people, who face higher risks depending on how many people are in the polyamorous group. •
Communication with sexual partners about sexual history and STI status, preferred safe sex practices, and
acceptable risks for partnered sexual activities. • Engaging in less-risky sexual activities. In general, solo sexual activities are less risky than partnered activities. Sexual penetration of orifices (mouth, vagina, anus) and sharing body fluids (such as semen, blood, vaginal fluids, and rectal mucus) between sexual partners carry a higher risk for STIs. • Regular STI testing and treatment, especially for those who are sexually active with more than one casual sexual partner. It is possible to attain and show proof of STI status from lab results. Some
online dating apps and websites allow this information to be shared. ==Ineffective methods==