Usnea mayrhoferi has a stiff, compact, and erect-shrubby appearance. Its branches are non-inflated and adorned with abundant , , and . The base of the trunk is distinctly blackened, and annular (ring-like) cracks extend along the basal branches.
Soralia (reproductive structures) are irregular and become large and excavate at the branch tips. The species has an opaque , a very thin
medulla, and a broad with an axis to medulla ratio greater than 4.5.
Usnea mayrhoferi is closely related to other species such as
Usnea krogiana,
U. brattiae, and
U. cedrosiana. However, it can be distinguished by its unique combination of characteristics, including its blackened trunk, crowded soralia, and broad axis. While some of these species share similar chemistry,
Usnea mayrhoferi has only been observed with a single
chemotype containing
norstictic acid. ==Habitat and distribution==