• Sir
Alan Sykes, 1st Baronet, businessman and British politician •
Annette Sykes, New Zealand human rights lawyer and Māori activist •
Bob Sykes (American football), American football player •
Bob Sykes (baseball), American baseball pitcher •
Bob Sykes (ice hockey), Canadian ice hockey player •
Bobbi Sykes, Australian author and land rights activist •
Bryan Sykes, British academic and geneticist •
Christopher Sykes (author), British author •
Christopher Sykes (politician), British politician •
Diane S. Sykes, judge on the United States Court of Appeals •
Edmund Sykes, Catholic martyr •
Emilia Sykes, American politician •
Eric Sykes, comedic writer and actor •
Eric A. Sykes, developer of the Fairbairn-Sykes fighting knife •
Ernest Sykes (VC), recipient of the Victoria Cross •
Ernest Ruthven Sykes (1867–1954), malacologist from Great Britain •
Eugene O. Sykes (1876–1945), justice on the Mississippi Supreme Court •
Frederick Henry Sykes (1863–1917), Canadian-American educator and college president • Sir
Frederick Hugh Sykes, British military officer and politician •
Gary Sykes, English Profesional boxer •
George Sykes, U.S. Army general •
Gresham Sykes (1922–2010), American sociologist and criminologist •
Homer Sykes, Canadian-born British photographer • Congressman
James Sykes (Continental Congress), lawyer and American politician • Governor
James Sykes (governor), physician and American politician •
John Sykes (1959–2024), English singer and guitarist •
John Sykes (American football) (1949–2019), American football player •
John Sykes (composer) (1909–1962), English composer and music teacher, born in India •
John Sykes (politician), British politician •
John H. Sykes Tampa Bay area businessman and founder of Sykes inc. •
Keifer Sykes (born 1993), American basketball player • Sir
Mark Sykes, British politician and diplomatic advisor •
Melanie Sykes (born 1970), English television and radio presenter, and model •
Nathan Sykes (born 1993), member of boy band
The Wanted •
Norman Sykes (1936–2009), English footballer •
Oliver Sykes, frontman of
Bring Me the Horizon •
Paul Sykes (boxer) (1946–2007), English heavyweight boxer of the 1970s and 1980s •
Paul Sykes (businessman) (born 1943), English Eurosceptic businessman, and political donor •
Paul Sykes (rugby league) (born 1981), rugby league footballer of the 1990s, 2000s and 2010s •
Paul Sykes (singer), American folksinger of the 1960s • Sir
Percy Sykes, British soldier, geographer and travel writer •
Peter Sykes (director) (1939–2006), Australian/British film director •
Peter Sykes (chemist) (1923–2003), British chemist • Sir
Richard Sykes (biochemist), businessman and university rector • Sir
Richard Sykes (diplomat), diplomat assassinated in 1979 •
Richard Sykes (rugby union), Rugby player and Dakota landowner •
Rod Sykes (1929–2025), Canadian politician from Alberta •
Ronald Sykes (1899–1977), British aviator •
Stephen Sykes (1939–2014), ecclesiologist •
Sykes family of Sledmere •
Tatton Sykes (disambiguation) •
Thomas Sykes (Mississippi politician), African-American legislator in Mississippi during Reconstruction •
Thomas A. Sykes, African-American legislator in North Carolina and Tennessee during Reconstruction •
Thomas Hardcastle Sykes, businessman •
Timothy Sykes (born 1981), penny stock trader •
Tom Sykes, British motorcycle racer •
Wanda Sykes, comedian and actress •
William Sykes (businessman) (1852–1910), English businessman • Colonel
William Henry Sykes, military officer, politician, and ornithologist •
William Robert Sykes, British railway signal engineer • Sykes, South African singer-songwriter ==Companies==