Villiers grew up mostly in London, where his father was
Master of the Mint, a post which gave him rooms at the
Tower of London. On 23 June 1623, when his childless great-uncle
Oliver St John (1559–1630) was created
Viscount Grandison in the
peerage of Ireland, the honour was made subject to a
special remainder that it would be inherited by the heirs male of St John's niece Barbara Villiers. This meant when St John died in December 1630, Villiers inherited his title. In 1638
Charles I knighted Grandison at
Windsor, together with the
Prince of Wales and
Thomas Bruce, 1st Earl of Elgin. During the 1639 and 1640
Bishops' Wars, he was commissioned as
colonel but does not appear to have seen action. When the
First English Civil War began in August 1642, Grandison raised a regiment of cavalry, which formed part of the
Royalist left wing at
Edgehill on 23 October. During the fighting,
Sir Edmund Verney was killed and the
Royal Standard captured but then recovered by three men led by
John Smith, an officer in Grandison's regiment. Smith was knighted on the field, becoming the last knight
banneret created in England, and promoted to major by Grandison; he was later killed at
Cheriton in 1644. At the
Storming of Bristol on 26 July 1643, Grandison led one of three
brigades or "tertia" commanded by
Prince Rupert of the Rhine. His unit made a series of attacks on Prior's Hill Fort and a redoubt at Stokes Croft, in the third of which he was wounded in the right leg. together with his cousin Edward St John, a son of his uncle
Sir John St John. Grandison was taken to Oxford where he died on 29 September, presumably of a fever related to the injury, since Hyde explicitly states the wound caused his death. As Grandison had no son, he was succeeded by a younger brother,
John Villiers. After the
Restoration, Grandison's only child, Barbara Villiers, became a
royal mistress of
King Charles II, in 1670 was created
Duchess of Cleveland, and became the ancestor of several noble families, including the
Dukes of Grafton. Grandison's mother, Barbara Lady Villiers, born about 1592, lived into her eighties and saw
the Restoration and the early years of her great-grandchildren. Lord Grandison's youngest brother,
Edward, was the father of
Edward Villiers, 1st Earl of Jersey, ==Lydiard portrait==