Wood began his professional career in the 2010–2011 national tour of
Spring Awakening as Melchoir Gabor. Between 2011 and 2012, he worked in regional theater productions of
The Little Mermaid and
Damn Yankees. In 2013, Wood made his first television appearances with the TV movie
Browsers and the
TNT series
Major Crimes. In August of the same year, it was announced Wood had joined the cast for the second season of
The CW's
The Carrie Diaries as Adam Weaver in a recurring role. In 2014, Wood joined the sixth season of
The Vampire Diaries in a recurring role, playing the villain Malachi "Kai" Parker. He left the series in 2015 to pursue other projects but returned to the role on two separate occasions. He reprised the role for three episodes during
The Vampire Diaries eighth and final season in 2017 and again in 2020 in a two-episode guest arc in the second season of the spinoff series
Legacies. In February 2015, Wood was cast in the pilot for the drama series
Containment, portraying Jake Riley, a police officer trapped inside a quarantine zone. The series was picked up to order by The CW in May. Upon reading the pilot script, he said "I was just really drawn to the concept of this confined storyline. The characters are put in life-or-death situations that are very real—not every show has that element of stakes at that level." The series consisted of 13 episodes, running from April 19 to July 16, 2016, with The CW confirming in May
Containment would not return for a second season. In that April it was also announced Wood had been cast in a 2-episode guest arc on the second season of the
PBS period drama
Mercy Street, reuniting with
Carrie Diaries costar
AnnaSophia Robb. On July 20, 2016, it was announced Wood had joined the cast of
Supergirl as a series regular in an undisclosed role, his fourth project with The CW. In August, executive producers confirmed he would be playing
Mon-El in the show's upcoming second season. After being cast, Wood sat down with executive producer
Greg Berlanti, who explained the character using musical theater references and as "a romantic sort of quietly good soul under this more frat boy exterior" Wood left the series at the end of the third season in 2018. He would briefly reprise the role for the 100th episode,"
It's a Super Life" in 2020, and in 2021 for the series finale, "
Kara." In 2019, Wood wrote, directed, and produced his first short film
The Stew, a comedy about a toxic marriage, starring
Supergirl costar
Melissa Benoist as the wife and
Carlos Valdes as the husband.
The Stew premiered on January 26, 2019 at the Vancouver Short Film Festival. In August of the same year, Wood's film was selected to screen at 2019
HollyShorts Film Festival, showing on opening night. In February 2020, it was announced Wood had been cast as Leo Steadman in the pilot for
Thirtysomething(else), a follow up series to the
ABC drama
Thirtysomething. In June, the network announced the series had not been picked up to air. Also in February 2020, Wood joined the voice cast for
Kevin Smith's
Masters of the Universe: Revelation series as
Prince Adam/He-Man. The first series was released in two parts in July and November 2021. Wood made his
Broadway debut on November 3, 2022 in the production of
Almost Famous playing Russell Hammond. The show closed on January 8, 2023 after mixed reviews and average audiences and grosses, playing a total of 30 previews and 77 shows. In March 2023, Wood released his second short film,
Snowshoe, on
YouTube. In addition to writing, directing, and producing the short, Wood starred opposite longtime friend
Grant Gustin. Wood shot the film in one long continuous take in
Whistler, British Columbia in March 2021. In January 2024, Wood reprised the voice role of Prince Adam/He-Man in
Masters of the Universe: Revolution, a sequel series to 2021's
Masters of the Universe: Revelation. In December 2024, it was announced Wood had been cast in
Duo, an in development series for
NBC. The project received a script commitment from the network, which is set to be written by Wood. He is also credited as a co-executive producer. ==Personal life==