While the first known mention of Zalishchyky is traced back to 1340, the village had already existed for some time, and given its proximity to a number of other prehistoric settlements, probably dates back to the
Cucuteni–Trypillia culture of late
Paleolithic antiquity. The 'original' Zalishchyky was actually founded in the area just outside of the modern town's borders, on the land that is now the Ukrainian village of
Dobrivliany (which existed as a subdivision of the modern city between 1981 and 1986). In 1469, this village was a peasant farming community under the name Zalissia () and later Zalishche () in the 15th century. In 1569, Zalishchyky was assigned to the
Podolian Voivodship, an administrative unit of the
Polish–Lithuanian Commonwealth, to which the town became a seat for their county in 1774. In 1578, the village officially adopted the name "Zalishchyky". In 1594,
Stanisław Żółkiewski raised an army in Zalishchyky and defended the locale from a
Tartar invasion. In 1669, the village was completely destroyed by
Turk invaders, and the survivors were almost wiped out under the rule of the sultan
Mehmed IV during the better part of the
Second Polish–Ottoman War. No battles or skirmishes actually occurred during this "revolt", instead peasants went on strike and lodged complaints to the district council from the government. The Austrian government took many measures to suppress the peasant discontent, and finally in July 1838 evacuated the district administration and started a riot in Zalishchyky, all the while torturing innocent civilians. Some were able to escape to areas such as
Tashkent thanks to
Soviet evacuations and
deportations during the war. In March 1944, the region was liberated by the Russians, before briefly returning to German control, during which many Jews were murdered by the panicking Nazis. After being liberated a second time by the
1st Ukrainian Front on 24 March, survivors and some of those deported returned to Zalishchyky. While the Nazi forces had been defeated, conditions hardly improved. While Moscow lauded the liberation of the city, even naming
a battle division after the city, Communist control soon proved to be worse than Nazi occupation in many ways. Starting less than a day after liberation, denizens of Zalishchyky were arrested by
SMERSH and presumably murdered by operatives of the
NKVD. In October, more than 800 citizens from Zalishchyky were forcibly drafted by the Soviets to so called
penal military units (,
Shtrafbaty) to fight in the
Baltic Offensive, less than 20 survived. After the war, the town was largely repaired, as industrial plants, buildings, and roads were rebuilt and recommissioned. In addition, canneries were widely re-established, leading to the opening of bakeries, dairy plants, corn-calibrating plants, as well as factories which produced textiles and other consumer goods. Quite a few of these industries lasted until the fall of the Soviet Union, after which they collapsed following the Ukraine's transition from the Soviet
planned economy. Nonetheless, the city's economy continues to be concentrated on
light industry, particularly the agrarian sector. In 2016, Zalishchyky celebrated the 250th anniversary of township under the Magdeburg Law with a holiday commemorating the city. A two-day long "Zalishchyky Fest" ensued. Concurrently, Zalishchyky's government has begun work on repairing infrastructure, such as asphalt repair, paved lighting, new lights, benches, litter bins, and a number of improvements to either of the city's local parks; one of which, the Zalishchyky Central Park, houses a number of historic monuments and rare species of flora. This park and
Zalishchyky Park which lies to the south are a Ukrainian national park. Until 18 July 2020, Zalishchyky was the administrative centre of
Zalishchyky Raion. The raion was abolished in July 2020 as part of the administrative reform of Ukraine, which reduced the number of raions of Ternopil Oblast to three. The area of Zalishchyky Raion was merged into Chortkiv Raion. == Archaeology and monuments ==