The tournament's fixtures were announced on 28 April 2021, and included a Friday night game – Wales hosting France in
round 4 – for the first time since the
opening match of the
2019 Six Nations Championship.
Round 1 Notes: •
Seb Davies (Wales) was originally named on the bench but was replaced by
Ben Carter prior to kick-off due to a back spasm. •
Mack Hansen (Ireland) and
Dewi Lake (Wales) made their international debuts. •
Ross Moriarty (Wales) earned his 50th test cap. ----
Notes: •
Ben White (Scotland) made his international debut. • Scotland achieved back-to-back wins against England for the first time since
1984. • Scotland retained the
Calcutta Cup. •
Tom Curry became England's youngest captain since
Will Carling against Australia in 1988. ----
Notes: •
Toa Halafihi,
Leonardo Marin,
Tommaso Menoncello and
Manuel Zuliani (all Italy) made their international debuts. • France retained the
Giuseppe Garibaldi Trophy.
Round 2 Notes • Wales retained the
Doddie Weir Cup. •
Jac Morgan (Wales) and
Rory Darge (Scotland) made their international debuts. •
Dan Biggar and
Jonathan Davies (both Wales) won their 100th test caps, including caps for the
British & Irish Lions. ---- ----
Notes: •
Andrea Zambonin (Italy) and
Ollie Chessum (England) made their international debuts. •
Ben Youngs made his 114th appearance for England, equalling
Jason Leonard's record as England's most-capped player. • England kept a clean sheet against Italy in the Six Nations for the first time.
Round 3 Notes: •
Hamish Watson (Scotland) was originally named to start, but was forced to withdraw the day before the match after testing positive for
COVID-19. He was replaced by
Nick Haining, whose place on the bench was taken by
Andy Christie. • Andy Christie (Scotland) made his international debut. • France reclaimed the
Auld Alliance Trophy, having lost it in
2020. ----
Notes: •
Manu Tuilagi (England) was originally named to start, but was forced to withdraw due to injury. His place in the starting line-up was taken by
Elliot Daly, who was replaced on the bench by
Joe Marchant. •
Ben Youngs made his 115th appearance for England to surpass
Jason Leonard's record as England's most capped international player. •
Kyle Sinckler (England) and
Alex Cuthbert (Wales) earned their 50th test caps. •
Courtney Lawes (England) and
Dan Biggar (Wales) became the sixth club mates (
Northampton Saints) in the history of the Championship to captain their countries against each other. ----
Notes: •
Michael Lowry (Ireland) made his international debut. • Italy played with 13 players from the 19th minute of the match due to World Rugby Law 3.20, which requires a team that is unable to continue with contested scrums as a result of a player being sent off to lose an additional player. This meant that no replacement was made for
Toa Halafihi. • Italy suffered their 100th defeat in the Six Nations Championship. • Referee
Nika Amashukeli became the first
Georgian and Tier 2 union official to referee in this Six Nations Championship.
Round 4 ----
Notes: •
Ben Vellacott (Scotland) and
Ange Capuozzo (Italy) made their international debuts. •
Ali Price (Scotland) earned his 50th test cap. •
Giosuè Zilocchi and
Manuel Zuliani (Italy) were originally named on the bench, but were later replaced by
Tiziano Pasquali and
Braam Steyn. • Scotland won the inaugural
Cuttitta Cup. ----
Notes • Ireland retain the
Millennium Trophy. • This was Ireland's biggest win over England at Twickenham since
1964, surpassing the 13-point margin in 1964. •
Charlie Ewels' red card was the quickest to be given (at 82 seconds) in Championship history.
Round 5 Notes: •
Alun Wyn Jones (Wales) made his 150th appearance, the first player to achieve this. •
Dan Biggar (Wales) became the seventh Welshman to earn his 100th test cap. •
Braam Steyn (Italy) earned his 50th test cap. •
Tiziano Pasquali (Italy) had been named on the bench but withdrew ahead of the game and replaced by
Filippo Alongi. •
Filippo Alongi (Italy) made his international debut. • Italy won in the Six Nations Championship for the first time since their victory over Scotland in
Edinburgh in
2015 (19–22), ending a 36–match losing streak in the Championship. • Italy defeated Wales for the first time since
2007, and achieved their first away victory against Wales. • Italy won against a Tier 1 nation for the first time since their victory over
South Africa in
2016 (20–18). ----
Notes: • Ireland won the
Triple Crown for the first time since
2018, and the first time at home since
2004. • Ireland retained the
Centenary Quaich. ----
Notes: • France won the Grand Slam title for the first time since
2010, the last time they won the Championship. • France ended a 12-year wait to reclaim the Championship, their longest ever period between titles since their first title in
1959. ==Player statistics==