Shortly after graduation, Myrin briefly moved to Chicago, where she became a member of the
Improv Olympic and later re-located to New York City and Los Angeles, where she was part of the same group. One of her memorable
standup comedian acts included a section of her own life experiences called ''Straight Outta Lil' Compton
. She later wrote a book of such life experiences, called Little Miss Little Compton: A Memoir''. Myrin's television credits include
Insatiable,
Insecure, ''
Grey's Anatomy, Conan, Orange Is the New Black, Hung, Key & Peele, Inside Amy Schumer, W/ Bob & David, Psych, Bones, Fresh Off the Boat, Suburgatory, 2 Broke Girls, Reno 911!, Shameless, Gilmore Girls, and Secret Chef
. She has appeared on Late Night with Conan O'Brien, The Howard Stern Show, WTF with Marc Maron, and RuPaul's Drag Race. Myrin is also the host of the iHeartRadio podcast Will You Accept This Rose?
about The Bachelor franchise and in 2022 debuted another iHeartRadio podcast Lady of the Road
celebrating female leaders with co-host Bridgerton'' director
Julie Anne Robinson. Myrin has appeared in many films, including the
Quentin Dupieux films
Wrong Cops and
Wrong, as well as
Bachelorette,
Kinsey,
Morning Glory, and others. As a writer, she has sold pilots to Adult Swim and MTV, along with writing the memoir
Little Miss Little Compton. She appeared on
Chelsea Lately over 100 times and was a regular panelist on
@midnight. Myrin starred in the 2016 production of
Steve Martin's play
Meteor Shower at the
Long Wharf Theatre. Her other theater credits include
Robert O'Hara's
Barbecue at
The Public Theater in
New York City, as well as the premiere of
John Ross Bowie's play about
The Ramones Four Chords and A Gun at the Bootleg Theater in
Los Angeles. Myrin was in the original
New York City production of
David Mamet's
Boston Marriage at the
Public Theater, and appeared in
Hay Fever directed by Darko Tresnjak at the
Westport Country Playhouse.
Mad TV Myrin officially joined the cast of
Mad TV in 2005 as a repertory performer from season 11 to its last episode on FOX in 2009 (Myrin didn't come back to the show for its revival in 2016). ==Personal life==