Staite's first high profile appearances as a child actor came in
television movies such as
CBC's
Liar, Liar in 1993 (which was later aired on
CBS in the United States that same year) and
ABC's
The Only Way Out. In 1995, she had a key guest-starring role in a third-season episode of
The X-Files, "
Oubliette". After appearing on
Are You Afraid of the Dark? (1994), Staite's first co-starring role on a television series was as Catalina, the ship's engineer, in the first season of the
Nickelodeon science fiction series
Space Cases in 1996. This was immediately followed by her role as Rebecca "Becca" Fisher on the 1995–1997
Disney Channel series
Flash Forward, a series in which Staite was the co-lead with
Ben Foster. In 2000, she was cast in a main role on the
FOX Family Channel drama series
Higher Ground. She was also a voice actress in the animated TV series
Mummies Alive! and
Sabrina: The Animated Series for
DIC Entertainment. Staite played
Kaylee Frye in the short-lived
television series Firefly and its subsequent 2005 film,
Serenity. She wrote a chapter in the book
Finding Serenity, called "Kaylee Speaks: Jewel Staite On
Firefly". She played the recurring role of Heidi Gotts in the television series
Wonderfalls in 2004. Staite played the role of head medical doctor
Jennifer Keller in the
Stargate SG-1 spinoff
Stargate Atlantis, making her one of three actors from the
Firefly series to move on to appear in a
Stargate series (the others being
Adam Baldwin, who appeared in the episode "
Heroes", and
Morena Baccarin, who played
Adria in the tenth season of
SG-1). She replaced
Paul McGillion (Dr.
Carson Beckett). In the fifth season of
Stargate, her character was changed from recurring status to part of the main cast. Before taking on the role as Dr. Keller, she previously played the
Wraith child Ellia in the
Stargate Atlantis episode "
Instinct". She also appeared in the 2010
Syfy film,
Mothman, under direction from Sheldon Wilson. Also in 2010, Staite guest-starred in an episode of
Warehouse 13 as the love interest of Sheldon (played by
Sean Maher, who played her love interest in
Firefly), and in 2011, she guest-starred on an episode of
Supernatural as a former love interest of Sam. In 2012, Staite was a series regular on
The L.A. Complex, in which she portrayed Raquel Westbrook, a struggling actress. The show aired in Canada on
CTV and
MuchMusic and in the U.S. on
The CW. She also appeared in an episode of
The Listener. Staite appeared in 10 episodes of the
AMC crime drama,
The Killing, as Detective Stephen Holder's girlfriend Caroline Swift, from 2013–2014. ==Personal life==