•
Adam Sharples (born 1954), British executive •
Charlie Sharples (born 1989), English rugby union footballer •
Eliza Sharples (1803–1852), British writer and lecturer on freethought, radical politics and women's rights •
Ellen Sharples (1769–1849), English painter •
George Sharples (1943–2020), English footballer •
James Sharples (disambiguation) •
Jeff Sharples (born 1967), Canada former National Hockey League player •
John Sharples (disambiguation) •
Katrina Sharples, New Zealand biostatistician and violist •
Kayla Sharples (born 1997), American soccer player •
Linda Sharples, British statistician •
Mike Sharples (born 1952), British academic •
Pamela Sharples, Baroness Sharples (1923–2022), wife of Richard Sharples •
Philip M. Sharples (1857–1944), American inventor and industrialist •
Pita Sharples (born 1941), Maori academic and politician •
Richard Sharples (1916–1973), British politician assassinated while Governor of Bermuda •
Robert Sharples (1913–1987), British musical conductor, composer and bandleader •
Robert Sharples (classicist) (1949–2010), English educator and authority on ancient Greek philosophy •
Rolinda Sharples (1793–1838), English painter •
Winston Sharples (1909–1978), American composer known for his work with animated shorts ==Fictional characters==