Porto Atsu arrived at
Porto at the age of 17. On 14 May 2011, he was called up by first-team manager
André Villas-Boas for a
Primeira Liga match against
Marítimo, but he did not leave the
bench. As with teammate
Kelvin, Atsu was sent on
loan to fellow league side
Rio Ave for the
2011–12 season. He made his debut in the competition on 28 August 2011, in a 0–1 home loss against
Olhanense. On 16 December 2011, Atsu opened the score at
Estádio da Luz against
Benfica in the 24th minute, but the hosts eventually won it 5–1. He returned to Porto for the
2012–13 campaign, starting in nine of his league appearances as they won the national championship for the third consecutive time.
Chelsea On 1 September 2013, Atsu agreed to join
Chelsea on a five-year contract, for a reported £3.5 million, being immediately loaned to Dutch club
Vitesse, for the rest of the 2013–14 season.
Loan to Vitesse On 6 October 2013, Atsu made his debut against
Feyenoord as a substitute, replacing
Kazaishvili in the 77th minute. He went on to provide an assist to
Mike Havenaar, but it was not enough to prevent a 2–1 loss for Vitesse. On 19 October, Atsu made his first start against
Heerenveen, which ended in a 3–2 win for Vitesse. On 9 November, he converted a penalty for his first goal with Vitesse, against
Utrecht; the match ended in a 3–1 win for Vitesse. In total, Atsu played 30 games and scored 5 goals for the Dutch side as they finished 6th in the
league and qualified to the
playoffs.
Loan to Everton On 13 August 2014, Atsu joined fellow Premier League club
Everton on loan until the end of the
2014–15 season. He made his first appearance for the club ten days later, coming on as an 85th-minute substitute for
Kevin Mirallas in a 2–2 draw with
Arsenal at
Goodison Park. Atsu made his first start in the league on 21 September 2014 against
Crystal Palace, which ended in a 2–3 home loss. After his absence due to the
Africa Cup of Nations, he returned to the line-up on 19 February 2015 in a Europa League match against
Young Boys, playing out the last five minutes after replacing hat-trick scorer
Romelu Lukaku. and came off the bench three days later to set up a late equaliser in a 2–2 draw at home to
Leicester City. On 15 March 2015, in the match against
Newcastle United, he came off the bench with five minutes remaining, and provided an assist to fellow substitute
Ross Barkley for Everton's third goal of a 3–0 home victory. Following Atsu's impact as a substitute in the above games, he was picked to start the second leg of a Europa League Round of 16 match away to
Dynamo Kyiv on 19 March with regular right-winger
Aaron Lennon cup-tied, with Everton leading 2–1 from the first leg. His team were eliminated after losing 5–2 on the night, he was withdrawn in the 65th minute, and that was his final first-team appearance for Everton.
Loan to Bournemouth On 29 May 2015, Atsu was loaned to newly promoted Premier League team
Bournemouth for the upcoming season, with club Chief Executive Neill Blake calling the deal "a huge coup". He made his debut on 25 August in the second round of the League Cup, starting in a 4–0 win at
Hartlepool United. Atsu's only other appearance was in the next round's victory at
Preston North End; he did not feature in any Bournemouth matchday squad in the league and he was recalled from his loan by Chelsea on 1 January 2016.
Loan to Málaga On 24 January 2016, Atsu gave an interview with the
BBC World Service in which he spoke about leaving Chelsea and his imminent transfer to
Levante. The next day, it was confirmed that he would be instead moving to
Málaga on loan. On 5 February 2016, Atsu made his debut in the starting eleven and scored in a 3–0 victory over
Getafe.
Newcastle United On 31 August 2016, Atsu joined
Newcastle United on a one-year loan deal with an option to buy clause in the contract. On 13 September, his debut for the club came on as a substitute for
Yoan Gouffran in the 61st minute in a 6–0 away victory against
Queens Park Rangers at
Loftus Road, where he provided the assist to
Aleksandar Mitrović to earn their fifth goal. Atsu scored his first goal for the club in a 1–0 win against
Rotherham United on 1 October, followed by further goals against
Cardiff City and
Wigan Athletic. In May 2017, Atsu signed a four-year deal to join Newcastle permanently for £6.2 million from Chelsea. He was released at its conclusion.
Al-Raed On 17 July 2021, Atsu joined
Al-Raed. Limited by injury, he played only eight games in the
Saudi Professional League.
Hatayspor On 6 September 2022, Atsu signed for
Süper Lig club
Hatayspor on an initial one-year contract with the option for a further year. He played three league games and one in the
Turkish Cup, and scored the only goal at home to
Kasımpaşa in the seventh minute of added time on 5 February 2023, the day before the earthquake that killed him. ==International career==