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Columella (auditory system), a part of the auditory system of amphibians, reptiles and birds •
Columella (botany), an axis of sterile tissue which passes through the center of the spore-case of mosses and a cellular layer near the tip of a plant's root cap •
Columella (gastropod), an anatomical feature of a coiled snail or gastropod shell •
Columella (genus), a genus of land gastropods in the family Vertiginidae •
Columella (plant), a cultivar of Dutch elm •
Columella nasi, the fleshy external end of the nasal septum • In corals, the central axis structure of a
corallite formed by the inner ends of the septa ==Other uses==