•
Doc Adams (1814–1899), American baseball player and executive •
Doc Adkins (1872–1934), American baseball player •
Doc Alexander (1897–1975), American NFL football player and coach •
Doc Amole (1878–1912), American baseball player •
Doc Ayers (1891–1968), American baseball player •
Darrel Baldock (1938–2011), Australian rules football player and coach and politician nicknamed "The Doc" •
Doc Baker (died c. early 1920s), African-American football player •
Doc Bass (1898–1970), American baseball player •
Doc Bennett (1891–1974), American baseball player and manager •
Doc Blanchard (1924–2009), American football player and fighter pilot •
Doc Casey (1870–1936), American Major League Baseball player and manager •
Matthew Clarke (Australian footballer) (born 1973), retired •
Doc Cook (baseball) (1886–1973), American Major League Baseball player •
L. J. Cooke (1868–1943), American college men's basketball coach •
Doc Crandall (1887–1951), American Major League Baseball player, the first used consistently as a relief pitcher •
Donald Dann (1949–2005), Australian Paralympic athlete •
Seán Doherty (Gaelic footballer) (born 1947), Irish former Gaelic football manager and player •
Ed Dougherty (born 1947), American golfer •
Doc Edwards (1936–2018), American Major League Baseball player •
Mike Emrick (born 1946), American hockey broadcaster •
Julius Erving (born 1950), American basketball player •
Doc Gautreau (1901–1970), American Major League Baseball player and manager •
Doc Gessler (1880–1924), American Major League Baseball player •
Dwight Gooden (born 1964), American Major League Baseball pitcher •
Doctor Greenwood (1860–1951), English footballer •
Roy Halladay (1977–2017), American Major League Baseball pitcher •
Dick Hoblitzell (1888–1962), American Major League Baseball player •
Arthur Irwin (1858–1921), Canadian-American Major League Baseball player and manager •
Jack Kearns (1882–1963), American boxing manager, most notably for Jack Dempsey •
Allan Kwartler (1917–1998), American sabre and foil fencer •
Doc Lawson (born 1958), American soccer player •
Doc MacKenzie (1906–1936), American race car driver •
Doc McJames (1874–1901), American baseball player and physician •
Walter Meanwell (1884–1953), college men's basketball coach •
Doc Medich (born 1948), American baseball player •
Cary Middlecoff (1921–1998), American golfer and dentist •
Donald Minnegan (1902–2002), coach and athletic director at Towson University •
Gil Morgan (born 1946), American golfer •
Harold Nicholls (1897–1977), New Zealand rugby football player •
Danell Nicholson (born 1967), American former boxer •
Donncha O'Callaghan (born 1979), Irish rugby union footballer •
Derek Pace (1932–1989), English footballer •
Doc Powers (1870–1909), American Major League Baseball player and physician •
Doc Prothro (1893–1971), American Major League Baseball player and manager and dentist •
Doc Redman (born 1997), American golfer •
Ross Reynolds (1887–1970), American Major League Baseball pitcher •
Doc Rivers (born 1961), American National Basketball Association player and coach •
Johnny Rutherford (baseball) (1925–2016), Canadian Major League Baseball pitcher •
Harry Sage (1864–1947), American Major League Baseball player •
Homer Smoot (1878–1928), American Major League Baseball player •
Gary Wiggins (1952–2008), Australian cyclist nicknamed "The Doc" •
Doc Wise (born 1967), American football player •
George Yeager (1874–1940), American Major League Baseball player == Arts and entertainment ==