Dr. Mario received generally positive reviews, although some parents were critical of the premise of medicine in a children's game. The Game Boy version received positive reviews from
Joystick and
Zero magazines, the latter comparing it favorably with
Tetris and
Connect Four while stating it is "easy to play and impossible to master". In the Japanese magazine
Famicom Tsūshin, the four reviewers said that while the game is similar to
Tetris, they still found it fun with one reviewer saying it was more fun to play as a two-player game. The same four reviewers also complimented the Game Boy version of the game, with one reviewer feeling that the game was slightly worse due to the lack of color on the Game Boy making it harder to decipher some gameplay elements. In Japan, copies were sold for the
Game Boy, for the
Famicom, and 248,045 for the
Game Boy Advance, for a total of 3,858,045 cartridges sold in Japan. In North America, copies were sold within six weeks of release. Worldwide, copies were sold for the Game Boy and for the
Nintendo Entertainment System, for a total of cartridges sold worldwide across all platforms.
Retrospective reception Allgame praised the NES version, stating that on its release, "when puzzle games were flooding the market,
Dr. Mario stands out as one of the best, combining a smooth learning curve, playful graphics and memorable tunes" and "fundamental concepts may be simple, but the addictive gameplay becomes progressively more complex as the speed increases and additional viruses are added."
Dr. Mario was rated the 134th best game on a Nintendo system in
Nintendo Powers Top 200 Games list, the 7th best
Mario game of all time on ''
ScrewAttack's Top 10, and the 51st best NES game of all time by IGN. IGN
also rated the soundtrack, composed by Hirokazu Tanaka, as seventh in its list of the top ten greatest 8-bit soundtracks. GamesRadar ranked it the 13th best NES game ever made, calling it "one of the most celebrated of the [puzzle] genre". Game Informers Ben Reeves called it the seventh best Game Boy game. In 2019, PC Magazine'' included Dr. Mario on their "The 10 Best Game Boy Games". The
Game Boy Advance re-release in the
Classic NES Series is rated 66/100 on
Metacritic based on 10 reviews. Craig Harris of
IGN sarcastically expressed unease over the game's use of medicine. He enjoyed the addictive gameplay, but criticized the
black-and-white manual which made it difficult to understand the colored gameplay mechanics.
Henk Rogers of the
Tetris Company spoke negatively about the game in an interview published in 2018, saying he "was pissed off about that game,
Dr. Mario was a blatant attempt to come up with a
Tetris replacement and I thought they did it in a cheesy way."
Legacy After the commercial success of
Dr. Mario, Nintendo released several follow-up games.
Dr. Mario 64, released in 2001 for the
Nintendo 64, features
Wario and several
Wario Land 3 characters, and offers numerous
game modes, including a story-focused
single-player mode. The game supports simultaneous
multiplayer for up to four players.
Dr. Mario 64 was subsequently released in Japan in
Nintendo Puzzle Collection for the
GameCube.
Dr. Mario Online Rx, released in 2008 on
WiiWare, offers
online multiplayer via
Nintendo Wi-Fi Connection.
Dr. Mario Express, released in 2009 for the
Nintendo DSi, does not support multiplayer gameplay.
Dr. Luigi was released in 2013 for the Wii U, with Luigi as a playable character, all the modes in
Dr. Mario Online Rx, and a new mode with L-shaped capsules. The latest installment,
Dr. Mario: Miracle Cure, was released in 2015 for the Nintendo 3DS, and introduced power-ups to the series.
Dr. Mario World was a
mobile game that was released on 2019 for iOS and Android smart devices, and features new mechanics, such as brand new doctors with special abilities, assistants, and a gacha system.
Dr. Mario World was discontinued in November 2021. Various games in the
Super Smash Bros. series have remixed musical tracks from
Dr. Mario, or Dr. Mario as an
unlockable playable character.
Dr. Wario replaces Mario with Wario, as an
unlockable minigame in
WarioWare, Inc.: Mega Microgames!. A simplified version of
Dr. Mario is in
Brain Age 2: More Training in Minutes a Day! as the "Virus Buster"
minigame, using the touch screen to drag the capsules around the playing field. The viruses are enemies in
Mario & Luigi: Superstar Saga and
Mario & Luigi: Dream Team. They change colors when attacked, and are all defeated when they are all the same color. In 2018, the
Classic Tetris World Championship featured a
Dr. Mario championship as a side event. ==References==