Ear

The human ear consists of three parts—the outer ear, middle ear and inner ear. The ear canal of the outer ear is separated from the air-filled tympanic cavity of the middle ear by the eardrum. The middle ear contains the three small bones—the ossicles—involved in the transmission of sound, and is connected to the throat at the nasopharynx, via the pharyngeal opening of the Eustachian tube. The inner ear contains the otolith organs—the utricle and saccule—and the semicircular canals belonging to the vestibular system, as well as the cochlea of the auditory system. The auricle consists of the curving outer rim called the helix, and the inner curved rim called the antihelix, and opens into the ear canal. The tragus protrudes and partially obscures the ear canal, as does the facing antitragus. The hollow region in front of the ear canal is called the concha. The ear canal stretches for about 1inch (2.5cm). The first part of the canal is surrounded by cartilage, while the second part near the eardrum is surrounded by bone. This bony part is known as the auditory bulla and is formed by the tympanic part of the temporal bone. The ear canal ends at the external surface of the eardrum, while the surrounding skin contains ceruminous and sebaceous glands that produce protective earwax. Earwax naturally migrates outward through the ear canal, constituting a self-cleaning system. Two sets of muscles are associated with the outer ear: the intrinsic and extrinsic muscles. In some mammals, these muscles can adjust the direction of the pinna. The ear muscles are supplied by the facial nerve, which also supplies sensation to the skin of the ear itself, as well as to the external ear cavity. The great auricular nerve, auricular nerve, auriculotemporal nerve, and lesser and greater occipital nerves of the cervical plexus all supply sensation to parts of the outer ear and the surrounding skin. The auricle consists of a single piece of elastic cartilage with a complicated relief on its inner surface and a fairly smooth configuration on its posterior surface. A tubercle, known as Darwin's tubercle, is sometimes present, lying in the descending part of the helix and corresponding to the ear-tip of mammals. The earlobe consists of areola and adipose tissue. The symmetrical arrangement of the two ears allows for the localisation of sound. The brain accomplishes this by comparing arrival-times and intensities from each ear, in circuits located in the superior olivary complex and the trapezoid bodies, which are connected via pathways to both ears. Middle ear The middle ear lies between the outer ear and the inner ear. It consists of an air-filled cavity called the tympanic cavity and includes the three ossicles and their attaching ligaments; the auditory tube; and the round and oval windows. The ossicles are three small bones that function together to receive, amplify, and transmit the sound from the eardrum to the inner ear. The ossicles are the malleus (hammer), incus (anvil), and the stapes (stirrup). The stapes is the smallest named bone in the body. The middle ear also connects to the upper throat at the nasopharynx via the pharyngeal opening of the Eustachian tube. The three ossicles transmit sound from the outer ear to the inner ear. The malleus receives vibrations from sound pressure on the eardrum, where it is connected at its longest part (the manubrium or handle) by a ligament. It transmits vibrations to the incus, which in turn transmits the vibrations to the small stapes bone. The wide base of the stapes rests on the oval window. As the stapes vibrates, vibrations are transmitted through the oval window, causing movement of fluid within the cochlea. The bony labyrinth refers to the bony compartment which contains the membranous labyrinth, contained within the temporal bone. The inner ear structurally begins at the oval window, which receives vibrations from the incus of the middle ear. Vibrations are transmitted into the inner ear into a fluid called endolymph, which fills the membranous labyrinth. The endolymph is situated in two vestibules, the utricle and saccule, and eventually transmits to the cochlea, a spiral-shaped structure. The cochlea consists of three fluid-filled spaces: the vestibular duct, the cochlear duct, and the tympanic duct. Hair cells responsible for transduction—changing mechanical changes into electrical stimuli are present in the organ of Corti in the cochlea. Blood supply The outer ear is supplied by a number of arteries. The posterior auricular artery provides the majority of the blood supply. The anterior auricular arteries provide some supply to the outer rim of the ear and scalp behind it. The posterior auricular artery is a direct branch of the external carotid artery, and the anterior auricular arteries are branches from the superficial temporal artery. The occipital artery also plays a role. The middle ear is supplied by the mastoid branch of either the occipital or posterior auricular arteries and the deep auricular artery, a branch of the maxillary artery. Other arteries which are present but play a smaller role include branches of the middle meningeal artery, ascending pharyngeal artery, internal carotid artery, and the artery of the pterygoid canal. The inner ear is supplied by the anterior tympanic branch of the maxillary artery; the stylomastoid branch of the posterior auricular artery; the petrosal branch of middle meningeal artery; and the labyrinthine artery, arising from either the anterior inferior cerebellar artery or the basilar artery. ==Functions==

Hearing Sound waves travel through the outer ear, are modulated by the middle ear, and are transmitted to the vestibulocochlear nerve in the inner ear. This nerve transmits information to the temporal lobe of the brain, where it is registered as sound. Sound that travels through the outer ear impacts on the eardrum, and causes it to vibrate. The three ossicles bones transmit this sound to a second window (the oval window), which protects the fluid-filled inner ear. In detail, the pinna of the outer ear helps to focus a sound, which impacts on the eardrum. The malleus rests on the membrane, and receives the vibration. This vibration is transmitted along the incus and stapes to the oval window. Two small muscles, the tensor tympani and stapedius, also help modulate noise. The two muscles reflexively contract to dampen excessive vibrations. Vibration of the oval window causes vibration of the endolymph within the vestibule and the cochlea. or ultrasound (above 20 kHz) Balance Providing balance, when moving or stationary, is also a central function of the ear. The ear facilitates two types of balance: static and dynamic balance, static balance allows a person to feel the effects of gravity, and dynamic balance allows a person to sense acceleration. Static balance is provided by two ventricles, the utricle and the saccule. Cells lining the walls of these ventricles contain fine filaments, and the cells are covered with a fine gelatinous layer. Each cell has 50–70 small filaments, and one large filament, the kinocilium. Within the gelatinous layer lie otoliths, tiny formations of calcium carbonate. When a person moves, these otoliths shift position. This shift alters the positions of the filaments, which opens ion channels within the cell membranes, creating depolarisation and an action potential that is transmitted to the brain along the vestibulocochlear nerve. Dynamic balance is provided through the three semicircular canals. These three canals are orthogonal (at right angles) to each other. At the end of each canal is a slight enlargement, known as the ampulla, which contains numerous cells with filaments in a central area called the cupula. The fluid in these canals rotates according to the momentum of the head. When a person changes acceleration, the inertia of the fluid changes. This affects the pressure on the cupula, and results in the opening of ion channels. This causes depolarisation, which is passed as a signal to the brain along the vestibulocochlear nerve. Dynamic balance also helps maintain eye tracking when moving, via the vestibulo-ocular reflex. ==Development==

During embryogenesis, the ear develops as three distinct structures: the inner ear, the middle ear and the outer ear. Each structure originates from a different germ layer: the ectoderm, endoderm and mesenchyme. Inner ear on a developing embryo (about four weeks old) develops (six weeks). Around its second to third week, the developing embryo consists of three layers: ectoderm, mesoderm, and endoderm. The first part of the ear to develop is the inner ear, This entire mass is eventually surrounded by mesenchyme to form the bony labyrinth. Around the 28th day, parts of the otic vesicle begin to form the vestibulocochlear nerve. These form bipolar neurons, which supply sensation to parts of the inner ear (namely the sensory parts of the semicircular canals, macular of the utricle and saccule, and organ of Corti). Middle ear The middle ear and its components develop from the first and second pharyngeal arches. Uniqueness Ears are individually almost unique, with the odds of two people having matching ears being very low. Additionally, the ear's proportions are normally retained for life, and have thus been employed for forensic identification since the 1950s. ==Clinical significance==

Hearing loss Normal hearing levels are 20 decibels, hearing less than this is either partial hearing loss or total hearing loss. This may be a result of injury or damage, congenital disease, or physiological causes. When hearing loss is a result of injury or damage to the outer ear or to the ossicles of the middle ear, it is known as conductive hearing loss. When hearing loss is a result of injury or damage to the inner ear structures such as the cochlea, auditory nerve, and potentially to the vestibulochoclear nerve, it is known as sensorineural hearing loss. A hearing aid may be used if the hearing loss (sensorineural) results from damage to the inner ear hair cells. Hearing aids work by amplifying the sound of the local environment. Congenital abnormalities Anomalies and malformations of the auricle are common. These anomalies include chromosome syndromes such as ring 18. Children may also present cases of abnormal ear canals and low ear implantation. with a cosmetic surgical procedure to reduce the size or change the shape of the ear is called an otoplasty. The initial medical intervention is aimed at assessing the baby's hearing and the condition of the ear canal, as well as the middle and inner ear. Depending on the results of tests, reconstruction of the outer ear is done in stages, with planning for any possible repairs of the rest of the ear. Approximately one out of one thousand children suffer some type of congenital deafness related to the development of the inner ear. Inner ear congenital anomalies are related to sensorineural hearing loss and are generally diagnosed with a computed tomography (CT) scan or a magnetic resonance imaging (MRI) scan. Injury Injuries to the external ear occur fairly frequently, and can leave minor to major deformity. Injuries include: laceration, avulsion injuries, burn and repeated twisting or pulling of an ear, for discipline or torture. Chronic damage to the ears can cause cauliflower ear, a common condition in boxers and wrestlers in which the cartilage around the ears becomes lumpy and distorted owing to persistence of a haematoma around the perichondrium, which can impair blood supply and healing. Owing to its exposed position, the external ear is susceptible to frostbite as well as skin cancers, including squamous-cell carcinoma and basal-cell carcinomas. The ear drum may become perforated in the event of a large sound or explosion, when diving or flying (called barotrauma), or by objects inserted into the ear. Another common cause of injury is due to an infection such as otitis media. These may cause a discharge from the ear called otorrhea, and are often investigated by otoscopy and audiometry. Treatment may include watchful waiting, antibiotics and possibly surgery, if the injury is prolonged or the position of the ossicles is affected. Skull fractures that go through the part of the skull containing the ear structures (the temporal bone) can also cause damage to the middle ear. A cholesteatoma is a cyst of squamous skin cells that may develop from birth or secondary to other causes such as chronic ear infections. It may impair hearing or cause dizziness or vertigo, and is usually investigated by otoscopy and may require a CT scan. The treatment for cholesteatoma is surgery. There are two principal damage mechanisms to the inner ear in industrialised society, and both injure hair cells. The first is exposure to elevated sound levels (noise trauma), and the second is exposure to drugs and other substances (ototoxicity). A large number of people are exposed to sound levels on a daily basis that are likely to lead to significant hearing loss. The National Institute for Occupational Safety and Health has recently published research on the estimated numbers of persons with hearing difficulty (11%) and the percentage of those that can be attributed to occupational noise exposure (24%). Furthermore, according to the National Health and Nutrition Examination Survey (NHANES), approximately twenty-two million (17%) US workers reported exposure to hazardous workplace noise. Tinnitus Tinnitus is the hearing of sound when no external sound is present. While often described as a ringing, it may also sound like a clicking, hiss or roaring. Most of the time, it comes on gradually. In some people, the sound causes depression, anxiety, or concentration difficulties. It is more common in those with depression and anxiety. ==Society and culture==

The ears have been ornamented with jewelry for thousands of years, traditionally by piercing of the earlobe. In ancient and modern cultures, ornaments have been placed to stretch and enlarge the earlobes, allowing for larger plugs to be slid into a large fleshy gap in the lobe. Tearing of the earlobe from the weight of heavy earrings, or from traumatic pull of an earring (for example, by snagging on a sweater), is fairly common. Injury to the ears has been present since Roman times as a method of reprimand or punishment – "In Roman times, when a dispute arose that could not be settled amicably, the injured party cited the name of the person thought to be responsible before the Praetor; if the offender did not appear within the specified time limit, the complainant summoned witnesses to make statements. If they refused, as often happened, the injured party was allowed to drag them by the ear and to pinch them hard if they resisted. Hence the French expression "", of which the literal meaning is "to have one's ear pulled" and the figurative meaning "to take a lot of persuading". We use the expression "to tweak (or pull) someone's ears" to mean "inflict a punishment"." The first surgery to reduce the projection of prominent ears was published in the medical literature by Ernst Dieffenbach in 1845, and the first case report in 1881. Pointy ears are a characteristic of some creatures in folklore such as the French croquemitaine, and Brazilian curupira. It has been a feature of characters on art as old as that of Ancient Greece and medieval Europe. Pointy ears are a common characteristic of many creatures in the fantasy genre, including elves, faeries, pixies, hobbits, or orcs. They are a characteristic of creatures in the horror genre, such as vampires. Pointy ears are also found in the science fiction genre; for example among the Vulcan and Romulan races of the Star Trek universe and the Nightcrawler character from the X-Men universe. Georg von Békésy was a Hungarian biophysicist born in Budapest, Hungary. In 1961, he was awarded the Nobel Prize in Physiology or Medicine for his research on the function of the cochlea in the mammalian hearing organ. The Vacanti mouse was a laboratory mouse that had what looked like a human ear grown on its back. The "ear" was actually an ear-shaped cartilage structure grown by seeding cow cartilage cells into a biodegradable ear-shaped mold and then implanted under the skin of the mouse; then the cartilage naturally grew by itself.{{Cite journal ==Other animals==

The ears of vertebrates are placed somewhat symmetrically on either side of the head, an arrangement that aids sound localization. All mammals have three auditory ossicles. The external pinna in therian mammals helps direct sound through the ear canal to the eardrum. The complex geometry of ridges on the inner surface of some mammalian ears helps to sharply focus sounds produced by prey, using echolocation signals. These ridges can be regarded as the acoustic equivalent of a Fresnel lens, and may be seen in a wide range of animals, including the bat, aye-aye, lesser galago, bat-eared fox, mouse lemur and others. Some large primates such as gorillas and orangutans (and also humans) have undeveloped ear muscles that are non-functional vestigial structures, yet are still large enough to be easily identified. An ear muscle that cannot move the ear, for whatever reason, has lost that biological function. This serves as evidence of homology between related species. In humans, there is variability in these muscles, such that some people are able to move their ears in various directions, and it has been said that it may be possible for others to gain such movement by repeated trials. In some animals with mobile pinnae (like the horse), each pinna can be aimed independently to better receive the sound. For these animals, the pinnae help localise the direction of the sound source. File:Elephant near ndutu.jpg| File:2009-03-07Vulpes zerda016.jpg| Image:Vulpes lagopus in Iceland.jpg| File:Rabbit - French Lop breed.jpg| The ear, with its blood vessels close to the surface, is an essential thermoregulator in some land mammals, including the elephant, the fox, and the rabbit. There are five types of ear carriage in domestic rabbits, some of which have been bred for exaggerated ear length—a potential health risk that is controlled in some countries. Abnormalities in the skull of a half-lop rabbit were studied by Charles Darwin in 1868. In marine mammals, earless seals are one of three groups of Pinnipedia. Invertebrates Only vertebrate animals have ears, though many invertebrates detect sound using other kinds of sense organs. In insects, tympanal organs are used to hear distant sounds. They are located either on the head or elsewhere, depending on the insect family. The tympanal organs of some insects are extremely sensitive, offering acute hearing beyond that of most other animals. The female cricket fly Ormia ochracea has tympanal organs on each side of her abdomen. They are connected by a thin bridge of exoskeleton and they function like a tiny pair of eardrums, but, because they are linked, they provide acute directional information. The fly uses her "ears" to detect the call of her host, a male cricket. Depending on where the song of the cricket is coming from, the fly's hearing organs will reverberate at slightly different frequencies. This difference may be as little as 50 billionths of a second, but it is enough to allow the fly to home in directly on a singing male cricket and parasitise it. Simpler structures allow other arthropods to detect near-field sounds. Spiders and cockroaches, for example, have hairs on their legs, which are used for detecting sound. Caterpillars of the Monarch butterfly have shown behavioral responses to airborne vibration (sound). Experiments have shown that the detection of sound is received through a pair of 450 micrometre long hairs called trichoid sensilla located on their upper prothorax. Response has been shown to the flight sounds of insect predators and parasitoids. ==See also==