•
Abby Epstein, American documentary director and producer •
Alex Epstein (writer) (born 1963), American Canadian writer and film producer •
Alex Epstein (born 1971), Israeli writer •
Alvin Epstein (1925–2018), American actor and director •
Asaf Epstein (born 1978), Israeli film director, writer, and producer •
Barbara Epstein (1928–2006), American literary editor •
Benita Epstein, American cartoonist •
Brett Epstein (born 1978), American musician, songwriter, and record producer •
Daniel Epstein (pianist) (born 1946), American pianist •
Daniel Mark Epstein (born 1948), American biographer and poet •
David Epstein (conductor) (1930–2002), American composer, conductor, and music scientist •
Deborah Epstein (born 1984), French-American singer-songwriter more commonly known as SoShy •
Dorrit Epstein (1917–2014), Czech British graphic designer •
Elisabeth Epstein (1879–1956), Russian painter •
Emily Rose Epstein, American drummer •
Freyda Epstein (1956–2003), American folk musician •
Gustav von Epstein (1828–1879), commissioned the Palais Epstein. •
Győző Epstein (1879–1945), Hungarian sculptor, graphic artist, and painter •
Hadassah Spira Epstein (1909–1992), American dancer •
Howie Epstein (1955–2003), American bass guitarist •
Jacob Epstein (1880–1959), American-British sculptor •
Jacob Epstein (writer), American television writer •
Jake Epstein (born 1987), Canadian actor •
Jason Epstein (1928–2022), American publisher who popularized the trade paperback •
Jean Epstein (1897–1953), French filmmaker •
Jennifer Cody Epstein, American novelist •
Jerome Epstein (director) (1922–1991), American filmmaker •
Josh Epstein, Canadian actor, producer and writer •
Joshua Epstein (violinist) (born 1940), Israeli musician •
Julius Epstein (1832–1926), Croatian pianist •
Julius J. Epstein (1909–2000), American screenwriter, brother of Philip G. Epstein •
June Epstein (1918–2004), Australian author, radio broadcaster, musician, and disability advocate •
Kalama Epstein (born 2000), American actor •
Kathie Lee Epstein (born 1953), maiden name of Kathie Lee Gifford, American television host •
Kathleen Epstein (1901–1979), American-British sculptor •
Lawrence J. Epstein (born 1946), American author •
Leslie Epstein (1938–2025), American novelist and essayist •
Marie Epstein (1899–1995), Polish-French actress and film preservationist •
Marti Epstein (born 1959), American composer •
Mel Epstein (1910–1994), American film director and producer •
Michael J. Epstein (born 1976), American filmmaker and musician •
Mitch Epstein (born 1952), American photographer •
Nicky Epstein, American knitting designer and author •
Peter Epstein (born 1967), American jazz saxophonist •
Philip G. Epstein (1909–1952), American Oscar-winning screenwriter, brother to Julius J. Epstein •
Rob Epstein (born 1955), American director •
Robin Epstein, American artist •
Sadie Kuttner Epstein (1883–1973), American concert singer •
Selma Epstein (1927–2014), American concert pianist •
Steven Epstein (music producer), U.S. classical music producer with Sony •
Ted Epstein, American drummer •
Temi Epstein (born 1975), American child actress •
Zale "Zalezy" Epstein, Canadian songwriter and musician == Business ==