As of 2015 there was a gold
artisanal mining camp at Muchacha within the reserve employing about 8,000 people. The mine was run by a loosely organized rebel faction,
Mai-Mai Simba, who aimed to liberate the local population from the reserve's land use restrictions. The warden of the reserve, Colonel Lucien Gedeon Lokumu announced operation to clear the reserve of rebel forces and mining operations. A June 2021 report from the United Nations Group of Experts on the Democratic Republic of the Congo raised concerns about the presence of semi-industrialized
dredging operations within the reserve, operating 12 kilometers south of Bandegaido. Mining took place within the Muchacha Ming Complex (MMC) which held a permit from the official DRC Mining Cadastre, held by the Chinese businessman Kong Maohuai's MCC Resources. The company Kimia Mining Investment Sarl was operating at the mine. Mining is illegal in the reserve, and
FARDC troops were guarding the mining site illegally. Later that month, Congolese authorities announced the seizure of 31 kg of gold (about $1.9 million) from this Muchaha mine. As of 2022, non-governmental organizations such as the Council for Environmental Defense through Legality and Traceability (CODELT) and Alerte Congolaise pour l'Environnement et les Droits de l'Homme (ACEDH) blame mining operations for destroying pristine rainforest within the reserve. ==Rebel attacks==