Early career Huffman made her debut on stage in 1982 and in the 1980s and 1990s worked as a rule on stage productions. In 1995, Huffman won
Obie Award for her performance in the play
The Cryptogram by David Mamet.
1991–2003: Earliest television and film roles in February 2010 Huffman debuted on the big screen in 1988 with a small role in Mamet's film
Things Change. Two years later, she appeared as Minnie, a Harvard law school student in the courtroom drama
Reversal of Fortune. Her other credits include 1992 thriller
Quicksand: No Escape with
Donald Sutherland and
Tim Matheson,
The Water Engine opposite William H. Macy, and supporting roles on
The Heart of Justice (1992),
Hackers (1995),
Harrison: Cry of the City (1996) and
The Underworld (1997). Huffman starred on the television mini-series
Golden Years, based on the novel by
Stephen King in 1991. In 1994, she starred in the ABC pilot
Thunder Alley as
Ed Asner's daughter, but was replaced in subsequent episodes by
Diane Venora when the series began. From 1998 to 2000, she portrayed Dana Whitaker in the series
Sports Night, for which she received several awards and nominations, including a
Golden Globe Award for Best Actress – Television Series Musical or Comedy. The series ended in May 2012, after eight seasons. In 2005, Huffman starred in the independent drama
Transamerica, playing Bree, a transgender woman who discovers that she had fathered a son who is now a troubled teen hustler on the run. In 2007, Huffman starred in
Garry Marshall's
Georgia Rule with
Jane Fonda and
Lindsay Lohan, and 2008 on independent drama
Phoebe in Wonderland. She made a film,
Lesster, as a writer, director and actress in 2010.
2013–present: Subsequent career and American Crime Huffman said that after seeing her as Lynette Scavo on
Housewives for eight years it was difficult for audiences to think of her as anything else. She said that's why she was eager for a role that's a distinctive departure. After
Desperate Housewives finale, Huffman reunited with playwright David Mamet in the comedy play
November. The play debuted on September 26 and ended on November 4, 2012. In 2012, she also appeared in the ensemble cast independent movie,
Trust Me, opposite
Clark Gregg. On February 15, 2013, Huffman signed on for the lead role of the
Fox drama pilot
Boomerang, directed by
Craig Brewer. The show centers on Margie Hamilton, a spy and master of disguise, who is the matriarch of the Hamilton clan, a "briskly professional assassin who can kill and dispose of a suspected terrorist in the afternoon – then switch to wife and mother mode without a hitch". However, Fox did not pick up
Boomerang as a new series. In 2013, Huffman starred in the independent drama
Rudderless, and in the adventure film
Big Game opposite
Samuel L. Jackson. She also starred in another independent drama
Stealing Cars, and was cast in the comedy film
Zendog. In April 2014 she appeared in the independent film
Cake opposite
Jennifer Aniston.In 2014, Huffman was cast as the lead in the ABC anthology legal drama pilot
American Crime created by
John Ridley. The pilot was picked up to series in May 2014. On October 2, 2014, it was announced that Huffman would be star and executive producer alongside
Carol Mendelsohn in her untitled drama about a special agent (Huffman) who is the fearless leader of a team of young agents on the New York City Joint Terrorism Task Force. The project was developed for ABC, but was not green-lighted for 2015–16 television season.
American Crime debuted on ABC in March, 2015 and Huffman received critical acclaim for her performance as an antagonistic character. Robert Bianco from
USA Today said in his review "A triumph for Oscar winner John Ridley, who created, produced and directed
American Crime, and a reconfirmation that Felicity Huffman is one of the best actors we have... In no case is that truer than with Huffman's Barb, who is the morally questionable center of the story. Barb is a Lifetime movie heroine: a tough, divorced mother who raised her children alone, and is fighting now to bring her son's murderer to justice. Except this isn't that kind of show, and Barb's battles have not just made her stronger; they've made her hate all the people she's felt she had to fight. Which is why Huffman's gut-wrenching performance is so startling. A bundle of barely concealed fury, Huffman forces us to invest in a woman who thinks her bigotry makes her not just right, but noble." In 2017, Huffman voiced a
parody of
herself in two episodes of the
Netflix animated series
BoJack Horseman. In 2018, Huffman starred in the second season of the
Epix comedy-drama
Get Shorty. In 2019, Huffman starred in two Netflix projects: the
Ava DuVernay miniseries
When They See Us about the famous
Central Park jogger case from 1989 in which a jogger was attacked in
Central Park in
New York City She also starred in the drama film ''
Tammy's Always Dying'' directed by
Amy Jo Johnson. which had its world premiere at the
Toronto International Film Festival in September 2019. It received generally positive reviews from critics, particularly for Huffman's and Phillips' performances. It was released through
video on demand on May 1, 2020, by
Quiver Distribution. In November 2020, it was reported that Huffman would star in an
ABC comedy television series pertaining to minor league baseball. However, the pilot was ultimately not picked up as a series. In March 2023, Huffman appeared in an episode of
The Good Doctor, in which she portrayed distinguished attorney Janet Stewart. Huffman was meant to reprise the role in a spin-off titled
The Good Lawyer; however, this spin-off was cancelled due to the
2023 Writers Guild of America strike. In 2025, she portrayed
Rena Chynoweth, a former
Mormon fundamentalist, in
The Thirteenth Wife: Escaping Polygamy, a limited series on
Lifetime. ==Personal life==