1920s SR 7 was established at least as early as 1919 on what is essentially its current path from the Florida state line southwest of
Statenville to Griffin. Between the end of 1921 and the end of 1926, US 41 was designated on SR 7 between the Florida state line and Perry; it was also designated on the Barnesville–Griffin segment. Five segments of SR 7 had a "completed hard surface": north-northwest of Valdosta, north-northwest of Adel, from the Cook–Tift county line to a point south-southeast of Tifton, north-northwest of Tifton, and the Barnesville–Griffin segment. Three segments had a "completed semi hard surface": from Florida to Valdosta, from north-northwest of Valdosta to Adel, and the Crisp County portion of the Cordele–Vienna segment. Two segments had a "sand clay or top soil" surface: from the Crisp–Dooly county line to the approximate location of Pinehurst and the entire Monroe County portion. Two segments were under construction: a portion in the south-southeast part of Tifton and from the approximate location of Arabi to Cordele. By the end of 1929, two segments had a completed hard surface: from Florida to Perry and a portion in the southeast part of Fort Valley. A very small portion from just south of the Crawford–Monroe county line had a sand clay or top soil surface.
1930s In the second half of 1930, two segments had a sand clay or top soil surface: from Fort Valley to northwest of the Peach–Crawford county line and from just south of the Crawford–Monroe county line to the Monroe–Lamar county line. Two segments were under construction: from the Florida state line to just northwest of the Echols–Lowndes county line and the Peach County portion of the Perry–Fort Valley segment. By the end of 1931, all of the highway from the Florida state line to just northwest of the Peach–Crawford county line, as well as the entire Monroe County segment had a completed hard surface. In February 1932, the entire Crawford County portion had a sand clay or top soil surface. By the middle of 1933, both the Crawford and Lamar county portions of the Roberta–Barnesville segment were under construction. In May, the Lamar county portion had completed
grading, but was not surfaced. By the end of 1935, nearly the entire Crawford County portion had a completed hard surface. In the first half of 1936, the Roberta–Griffin segment was also completed. In the second quarter of 1937, the entire highway was completed. By October, US 41's path from Perry to Barnesville, via Macon, was shifted west onto SR 7. By the end of the year, US 41 was reverted to its former path. Between February 1948 and April 1949, US 341 was designated on the Perry–Barnesville segment of SR 7.
1960s to 2000s Between June 1963 and the end of 1965,
SR 333 was proposed to be extended on a path that functioned like a
bypass. This extension was planned to extend south from the western part of Griffin, then south and southeast to US 41/SR 7 at Milner, then south-southeast and south-southwest to Aldora, and finally east-southeast to just south of Barnesville. In 1967, US 341/SR 7 in the Barnesville area was shifted southwest onto the southern part of this planned extension's path, along with SR 333. The former path of SR 7 northwest of Barnesville, on US 41, was redesignated as
SR 7 Conn., while the rest of it was under construction. The next year, SR 333 was extended on its planned path through Milner to US 19/SR 3 south-southwest of Griffin. In 1969, SR 333 was extended on US 19/US 41 to the southern part of Griffin. SR 7 was extended northwest to US 19/US 41/SR 3/SR 333, at the southern terminus of US 19 Bus./US 41 Bus. In 1970, SR 333 was truncated out of the Griffin area. SR 7 was extended on US 19/US 41 from south-southwest of Griffin to northwest of
Lovejoy. In 1981, SR 7 between a point north-northwest of Valdosta to Hahira was shifted west onto I-75 and SR 122, replacing
SR 7 Conn. The next year, US 41 was also shifted westward on this same path. In 1986, the northern terminus was reverted to its current point. In 2006, US 41/SR 7 was shifted out of downtown Valdosta, onto Inner Perimeter Road. The former path was redesignated as
US 41 Bus./
SR 7 Bus. The next year, US 41/SR 18 in the eastern part of Barnesville was rerouted on an eastern bypass of the city, which truncated US 341/SR 7 to the current northern terminus. ==Major intersections==