. In , the reigning
Parthian king
Artabanus II () died, entrusting his realm to his son
Vardanes I. However, the throne was seized by Gotarzes II, an adopted son of Artabanus II. Gotarzes had another of his brothers, Artabanus, along with his wife and child, executed shortly after. An uproar against this execution shortly followed, with an appeal being sent to Vardanes, who took Gotarzes by surprise and defeated him, after travelling 375 miles in two days. Vardanes was applauded by the governors of the neighbouring Parthian provinces, and quickly gained control over most of the Parthian realm. The
Mesopotamian city of
Seleucia, which had been in rebellion since 35, did not acknowledge Vardanes, who soon besieged the city. However, the long siege of Seleucia resulted in Gotarzes gaining the upper hand in the conflict, allowing him to raise a new force and drive off Vardanes, who fled to
Bactria in
Central Asia. At the same time,
Armenia suffered turmoil, when its
Arsacid king
Orodes, the brother of Vardanes, was deposed by the
Roman emperor
Claudius (), who appointed the
Pharnavazid prince
Mithridates in his stead. Simultaneously, just before Vardanes and Gotarzes clashed in battle, they reached an accord after Gotarzes informed Vardanes of a conspiracy being planned against them by a prominent group. The accord was that Vardanes was to keep his crown, while Gotarzes withdrew to
Hyrcania. Encouraged by his other recent triumphs, Vardanes prepared to invade and reconquer Armenia, but ultimately abandoned his plans, due to threats of war from the Roman governor of
Syria,
Gaius Vibius Marsus, along with renewed conflict with Gotarzes, who terminated their accord. Vardanes defeated Gotarzes on the Erindes, a river situated on the
Media-Hyrcania border. He then proceeded to conquer the remaining Parthian provinces, reaching as far as
Aria. In he was assassinated while hunting at the instigation of a party of Parthian nobles who feared that their status might become endangered. Soon afterwards Gotarzes II died (according to
Tacitus, of an illness, although
Josephus stated that he was murdered). His last coin is dated from June 51. Gotarzes II was succeeded briefly by his uncle
Vonones II and then by the latter's son,
Vologases I. ==In fiction==