Historically, the Great Valley has created a natural westward route from the
Philadelphia area to
Pennsylvania Dutch Country. The
Reading Company formerly operated the Chester Valley Branch, a line that ran through the valley from Downingtown to Bridgeport. The Chester Valley Railroad also operated on the line. After both railroads ceased operations, the right of way was eventually acquired by
Conrail and later abandoned. The
Pennsylvania Railroad's
Main Line formerly ran through the valley, running from the western end of the valley in Atglen and heading east before exiting in East Whiteland Township. Today, the same line is used as part of
Amtrak's
Keystone Service, which runs from
Philadelphia to
Harrisburg, and by
SEPTA's
Paoli/Thorndale Line, running from Philadelphia to Thorndale. Both the
Pennsylvania Turnpike and
U.S. Route 202 parallel each other through the eastern portion of the valley. The Pennsylvania Turnpike enters the valley from the northern hills in Devault and continues east until it reaches the valley's eastern end at the Schuylkill River. US 202 enters the valley through the southern hills in Glenloch and similarly runs east through the valley to the Schuylkill River.
U.S. Route 30 and its auxiliary,
U.S. Route 30 Business, run east–west through the valley as well. US 30 mainline enters from the north near Thorndale and runs east before leaving the valley in East Whiteland Township and heading south. US 30 Business enters the valley from the north in Coatesville and runs parallel to US 30 to Glenloch, where its designation ends. The historic
Lincoln Highway, concurrent with the
Philadelphia and Lancaster Turnpike in the area, follows US 30 Business from Coatesville to Glenloch, then along US 30 from Glenloch to East Whiteland Township.
Pennsylvania Route 372 serves as the main east–west highway for the far western portion of the valley, running from Atglen east to Coatesville. Highways that run north–south through the valley include:
PA 41 in Atglen,
PA 10 in Parkesburg,
PA 82 in Coatesville,
PA 340 in Caln Township,
US 322,
PA 282, and
PA 113 in Downingtown,
PA 100 in West Whiteland Township,
PA 401,
PA 352, and
PA 29 in East Whiteland Township,
PA 252 in Tredyffrin Township, and
US 422,
I-76,
PA 23, and
PA 320 in Upper Merion Township. ==References==