Western segment Ohio The western section of US 422 begins at
US 6 and
US 20 at the center of
Cleveland's
Public Square in the downtown district. US 422 and
SR 14, which shares its western terminus with that of US 422, form a
concurrency as the roadway heads south from the square. Less than a mile from the Public Square, US 422 and SR 14 intersect the Cleveland
Innerbelt, the confluence of
Interstate 90 (I-90) and the northern termini of
I-71 and
I-77. US 422 and SR 14 split at the interchange as SR 14 turns south to join
SR 43.
SR 8 begins at the eastern terminus of the US 422/SR 14 overlap, forming a concurrency with US 422 along Woodland Avenue. US 422 runs easterly along Woodland Avenue and Kinsman Road, through the Kinsman neighborhood. As it crosses Cleveland's city limits just west of Lee Road in
Shaker Heights, the street name changes to Chagrin Boulevard, named for the
Chagrin River and Chagrin Falls (the eastern terminus of the boulevard) in Cleveland's eastern suburbs. Today, US 422 in Shaker Heights and
Beachwood, where it now merges with I-271, is almost a linear
edge city, with millions of square feet in office space centered on this corridor. It is one of the busiest streets in
Cuyahoga County and
Greater Cleveland.
Eastern segment Dauphin and Lebanon counties The eastern section of US 422 begins at a
partial cloverleaf interchange with
US 322 and the eastern terminus of
PA 39 east of the borough of
Hummelstown in
Derry Township,
Dauphin County, heading northeast as a four-lane
freeway that soon ends and becomes an at-grade
divided highway called West
Chocolate Avenue. The road passes commercial development along with some farm fields and residential development as it heads into the community of
Hershey. The route heads into a mix of homes and businesses and turns east-northeast, where it narrows to a two-lane undivided road. At this point, West Chocolate Avenue becomes lined with
street lamps that are shaped like
Hershey's Kisses. US 422 continues along West Chocolate Avenue and comes to an intersection with
PA 743 at Cocoa Avenue in the center of Hershey. At this point, the route becomes East Chocolate Avenue, a three-lane divided with two eastbound lanes and one westbound lane that passes southeast of the site of the original
Hershey Chocolate factory. The road becomes undivided, still with two eastbound lanes and one westbound lane, and passes near a few residences and businesses as it heads between the
Hershey Country Club to the north and Spring Creek Golf Course to the south, narrowing to two lanes. US 422 runs past more residential and commercial development, leaving Hershey and heading through the community of
Palmdale. US 422 enters the borough of
Palmyra in
Lebanon County and becomes West Main Street, running past homes and a few businesses. The route heads into the downtown area and the name changes to East Main Street at the Railroad Street intersection. The road runs past residences before it passes through commercial areas and comes to an intersection with the northern terminus of
PA 117. US 422 gains a
center left-turn lane and continues past businesses, leaving Palmyra for
North Londonderry Township and becoming Benjamin Franklin Parkway. The route bends east and passes between businesses to the north and residential development to the south before it heads into farmland and crosses Killinger Creek, where it becomes the border between
North Annville Township to the north and
South Annville Township to the south as West Main Street. The road heads through agricultural areas with some woods, homes, and businesses, crossing the
Quittapahilla Creek into
Annville Township. At this point, US 422 heads east as a two-lane road that is lined with homes. In the commercial center of
Annville, the route crosses
PA 934 and becomes East Main Street, heading south of the
Lebanon Valley College campus. The road continues east past residential areas with a few businesses, gaining a center left-turn lane. US 422 heads into the borough of
Cleona and becomes West Penn Avenue, heading past homes and commercial establishments. The route becomes East Penn Avenue at the Center Street intersection and runs through more developed areas, becoming the border between Cleona to the north and
North Cornwall Township to the south. The road becomes the boundary between
North Lebanon Township to the north and North Cornwall Township to the south and the name changes to Cumberland Street. US 422 heads east past businesses and passes to the south of the
Lebanon Valley Mall. The route runs along the border between
West Lebanon Township to the north and North Cornwall Township to the south as it continues through commercial areas with a few homes. US 422 enters the city of
Lebanon at the 16th Street intersection, where it becomes a four-lane undivided road that passes commercial development and encounters an abandoned railroad line at the north end of the
Lebanon Valley Rail Trail. At 12th Street, the route crosses Quittapahilla Creek and splits into a
one-way pair following Cumberland Street westbound and Walnut Street eastbound, with each street carrying two lanes of traffic. US 422 continues east past urban
rowhouses along with a few businesses, intersecting the southbound direction of
PA 72 at 10th Street and the northbound direction of PA 72 at 9th Street. The westbound direction heads through the downtown area of Lebanon, passing south of the
Harrisburg Area Community College Lebanon Campus, while the eastbound direction heads through residential areas to the south of downtown. Farther east, US 422 passes urban areas of homes and businesses in the eastern part of Lebanon, with the eastbound direction passing north of WellSpan Good Samaritan Hospital. On the eastern border of Lebanon, the route comes to an intersection with the northern terminus of
PA 897. At this, westbound US 422 becomes the border between Lebanon to the north and
South Lebanon Township to the south, briefly becoming a three-lane divided highway with two westbound lanes and one eastbound lane between PA 897 and North 5th Avenue before becoming a one-way road again, while eastbound US 422 fully enters South Lebanon Township, heading past residential areas in the community of
Hebron. Eastbound US 422 turns north and passes businesses, crossing Quittapahilla Creek and rejoining westbound US 422 at East Cumberland Street. At this point, US 422 heads northeast as four-lane undivided East Cumberland Street past businesses, passing through a corner of Lebanon before entering North Lebanon Township and coming to a bridge over
Norfolk Southern's
Harrisburg Line as it passes north of the community of
Avon. The route becomes a three-lane road with a center left-turn lane and runs along the border between North Lebanon Township to the northwest and South Lebanon Township to the southeast, heading through residential areas in the community of Avon Heights. The road heads into a mix of farmland and residential and commercial development. US 422 enters
Jackson Township and becomes West Lincoln Avenue, crossing the
Tulpehocken Creek and continuing through agricultural areas with some homes and businesses. The route heads into business areas and enters the borough of
Myerstown, where it reaches an intersection with the southern terminus of
PA 645. The road becomes a four-lane divided highway and crosses
PA 501 before becoming East Lincoln Avenue at the Railroad Street intersection. US 422 leaves Myerstown for Jackson Township again and becomes a three-lane road with a center turn lane, heading east through farmland with some commercial development. The road intersects Wintersville Road/Millardsville Road, where it briefly become a divided highway before regaining a center left-turn lane. At this interchange, US 422 becomes
concurrent with US 222, and the two routes continue east-northeast along the six-lane
Warren Street Bypass, a
freeway that runs between residential areas to the northwest and Norfolk Southern's Harrisburg Line to the southeast. The freeway curves north into business areas and comes to a partial cloverleaf interchange with State Hill Road. Following this, US 222/US 422 passes between the
Berkshire Mall to the west and commercial areas to the east before it reaches an interchange with Paper Mill Road and Crossing Drive, where it curves to the northeast and runs near more businesses. The freeway comes to an interchange where US 222 splits to the northwest, US 422 immediately afterward splits southeast along the West Shore Bypass, and, straight ahead,
PA 12 begins northeast along the Warren Street Bypass. Following this interchange, US 422 heads southeast along the West Shore Bypass, a four-lane freeway that runs between residential areas to the southwest and the Tulpehocken Creek to the northeast. The road passes under Norfolk Southern's
Reading Line and comes to a
diamond interchange with North Wyomissing Boulevard. The route follows the west bank of the
Schuylkill River as it continues southeast and passes under Norfolk Southern's Harrisburg Line #2, crossing into the borough of
West Reading. US 422 runs between the river to the northeast and Norfolk Southern's Harrisburg Line #1 to the southwest before reaching a
cloverleaf interchange with US 422 Bus. Following this, the freeway heads south between the Schuylkill River to the east and industrial areas to the west, passing through a small
exclave of
Cumru Township and crossing over the
Schuylkill River Trail. The road curves southeast and crosses
Wyomissing Creek into the city of
Reading, where it runs along the riverbank and comes to an interchange with
US 222 Bus. that has left exits and entrances. From here, the route heads southeast between wooded areas near the Schuylkill River to the northeast and the Schuylkill River Trail and urbanized areas to the southwest. The freeway turns east and crosses the river into Cumru Township, where it passes through woodland and comes to a bridge over Norfolk Southern's Harrisburg Line. US 422 crosses the Schuylkill River again and reaches a
trumpet interchange with the northern terminus of
I-176. The road crosses the river a third time and enters
Exeter Township, passing over Norfolk Southern's Harrisburg Line #2 and running between residential areas to the north and industrial areas to the south before reaching an eastbound exit and westbound entrance with Neversink Road that provides access to the borough of
Mount Penn. From here, US 422 passes near more development before it comes to a westbound exit and eastbound entrance with the eastern terminus of US 422 Bus., at which point the freeway ends. At this point, the route enters
North Coventry Township in
Chester County and runs between woods to the north and farm fields to the south before passing near development and coming to a cloverleaf interchange with
PA 100. Past this interchange, the road heads through the community of
South Pottstown, which is across the river from the borough of Pottstown, and comes to a westbound exit and eastbound entrance with South Hanover Street. US 422 passes through woodland and reaches an eastbound exit and westbound entrance at Keim Street. A short distance later, the route comes to a trumpet interchange connecting to PA 724 to the south in the community of
Kenilworth. From here, the road turns northeast and crosses the Schuylkill River into
Lower Pottsgrove Township in Montgomery County, reaching a diamond interchange with Armand Hammer Boulevard in an industrial area. The freeway passes over Norfolk Southern's Pottstown Industrial Track and Harrisburg Line before running near residential and commercial development and turning to the east. US 422 heads between the community of
Sanatoga to the north and woodland to the south before it reaches a partial cloverleaf interchange with Evergreen Road that provides access to Sanatoga. This interchange marks the end of the Pottstown Bypass designation of the US 422 freeway. From here, the four-lane US 422 freeway continues southeast as the Pottstown Expressway into
Limerick Township and passes between the
Philadelphia Premium Outlets to the southwest and
Heritage Field Airport to the northeast, with the
Limerick Generating Station, a nuclear power plant, located further to the southwest. The road runs near a mix of farmland and residential and commercial development, coming to a diamond interchange with Lewis Road that provides access to the communities of
Limerick and
Linfield. A
park and ride lot is located within the southwest quadrant of this interchange. The route continues near more suburban development and reaches a diamond interchange with Township Line Road in a commercial area that serves the borough of
Trappe to the northeast and the borough of
Royersford to the southwest. Past this interchange, the freeway enters
Upper Providence Township and continues southeast past suburban housing developments. US 422 passes over
PA 113 without an interchange before coming to a partial cloverleaf interchange with
PA 29 that serves the borough of
Collegeville to the northeast and the borough of
Phoenixville the southwest. The
Providence Town Center lifestyle center is located along PA 29 north of this interchange. Following this interchange, the road runs near office parks before heading through wooded areas with some farm fields, with the median widening. The route passes near housing developments and office complexes before the median narrows and it curves to the south. The freeway comes to a partial cloverleaf interchange with Egypt Road in the community of
Oaks. From here, US 422 passes between a commercial area that includes the 422 Business Center office park (where the
American Treasure Tour is located) and the
Greater Philadelphia Expo Center to the west and the Lower Perkiomen Valley Park to the east. The road crosses the
Perkiomen Trail and the
Perkiomen Creek into
Lower Providence Township and becomes parallel to the Schuylkill River Trail to the west, making a sharp turn to the east and passing through woods and fields within
Valley Forge National Historical Park. The route comes to a partial cloverleaf interchange with the southern terminus of
PA 363 that provides access to the communities of
Audubon and
Trooper, where it enters
West Norriton Township and makes a turn to the south, gaining a third auxiliary lane in each direction. US 422 heads over the Schuylkill River Trail before it crosses the Schuylkill River on the Schuylkill River Crossing Complex east of the parallel
Sullivan's Bridge into
Upper Merion Township, where it becomes the County Line Expressway. The freeway passes over Norfolk Southern's Harrisburg Line before reaching a partial cloverleaf interchange with
PA 23 to the east of the Visitor Center at Valley Forge National Historical Park. From here, the route heads into the community of
King of Prussia as a four-lane freeway and passes to the west of business parks and the
Valley Forge Casino Resort, coming to an eastbound exit and entrance with First Avenue that serves the business parks and the casino. At this point, the road enters
Tredyffrin Township in Chester County and runs a short distance west of the border with Upper Merion Township in Montgomery County. The freeway passes under the
Pennsylvania Turnpike (
I-76) and heads near commercial areas west of the Village at Valley Forge, a residential and retail development which contains the
King of Prussia Town Center lifestyle center. US 422 comes to its eastern terminus at a trumpet interchange with the
US 202 freeway that also has ramps connecting to Swedesford Road and
I-76 eastbound to the city of
Philadelphia. US 202 northbound provides access from US 422 to I-76 westbound and the Pennsylvania Turnpike at the western terminus of I-276 at the
Valley Forge interchange along with the
King of Prussia shopping mall. ==History==