Acting In 1997, Grenier left Bard to embark on a film career. He made his film debut in the independent drama
Arresting Gena, then in 1999 played opposite
Melissa Joan Hart in
Drive Me Crazy and in 2001 starred in
James Toback's
Harvard Man. In 2004, Grenier played
Vincent Chase in the HBO series
Entourage, gaining his most substantial notability and success. The series followed the triumphs and trials in the life of Chase, as the movie star character and his friends lived the good life in Los Angeles. It ran for eight seasons, from 2004 to 2011, and was nominated for numerous
Emmy Awards, including Outstanding Comedy Series. In 2006, he starred alongside
Meryl Streep,
Anne Hathaway,
Emily Blunt,
Stanley Tucci and
Simon Baker in the comedy-drama
The Devil Wears Prada as Nate Cooper, a cook and the boyfriend of Hathaway's character, Andrea "Andy" Sachs. In 2013, he starred in the
post-apocalyptic film
Goodbye World alongside
Gaby Hoffmann. It premiered at the 2013
Los Angeles Film Festival where it received good reviews. The film made its cinematic release in the United States on April 4, 2014. Grenier stepped back in front of the camera in 2015 to reprise his role of Vincent Chase in the
Entourage film adaptation. Filming began in January 2014, and the film was released in June 2015. In 2016, Grenier shot the heist movie
Marauders. The film would make it to Netflix's American platform's top two in December 2020. Grenier also starred in the 2021 8-episode American-Australian drama/thriller miniseries,
Clickbait, on Netflix, where he played Nick Brewer. He is a campus advisor for Academy for Global Citizenship in Chicago, Illinois.
Directing and producing As a vehicle for Grenier to transition between acting, directing, and producing, with some partners, he started Reckless Productions in 2001. The company focused on producing socially-minded films. One of its first,
Shot in the Dark, chronicled Grenier's journey to reconnect with his estranged father, Dunbar, with whom his mother broke up when he was still a baby. Grenier and Dunbar remained estranged for 18 years until he began work on the documentary in an attempt to forge a relationship with him. The two eventually reunited and continue to remain in contact. This was Grenier's directorial debut, and the film premiered at the 2002
Tribeca Film Festival. HBO distributed the documentary and it premiered on the channel on June 3, 2007. On June 2, 2008, Grenier premiered a new television series,
Alter Eco, for which he was the producer. The show aired on the Discovery communications channel
Planet Green and featured Grenier and a team of green experts showing changes that can be made to live a more eco-friendly and sustainable lifestyle. On September 27, 2010, HBO premiered
Teenage Paparazzo, a documentary directed by Grenier and produced by Bert Marcus. It premiered at the
Sundance Film Festival. The film focused on 13-year-old paparazzo Austin Visschedyk and the celebrity-obsessed world in which he operates. It also featured interviews with celebrities such as
Lindsay Lohan,
Alec Baldwin, and
Whoopi Goldberg. Aside from HBO,
Teenage Paparazzo premiered on 40 other outlets around the globe. In addition to its theatrical release, Grenier took the documentary to college campuses nationwide in the Teenage Paparazzo Experience Tour. The tour included a call for art to be included in a traveling gallery that challenged the traditional understanding of celebrity and modern media. In 2010, Grenier began working as a producer alongside producer Bert Marcus and director
Matthew Cooke on the full-length feature documentary
How to Make Money Selling Drugs. The film was a tongue-in-cheek look at what is considered to be one of the worst domestic policy failures in recent American history. It featured actual dealers and celebrities commenting on the subject, including;
50 Cent,
Eminem,
Susan Sarandon and
David Simon, head writer of the HBO series
The Wire. It was released in the Summer of 2013 on Amazon.com and iTunes, and it received positive reviews.
Music Grenier plays guitar, bass, drums, and harmonica. He was a member of two New York bands: the lead singer in Kid Friendly and the drummer in The Honey Brothers before moving on to build Wreckroom, a music incubator, and recording studio in May 2012. Wreckroom releases EPs and a video series of cover songs, titled "Under the Covers". Two bands, Missouri "punk 'n' roll" trio
Radkey and metal-spined Brooklyn five-piece The Skins, released EPs on the label in 2013. Wreckroom also hosts curated music showcases in both Brooklyn and Austin. Most recently, Adrian co-wrote the song 'the master and margarita' with artist 'SORAYA'. The song was inspired by the
Russian surrealist classic novel of the same name but SORAYA and Adrian imagined it taking place in contemporary Austin, Texas. It was distributed by
Empire and released in early 2024. == Philanthropic efforts ==