• Josélito "Tito" Escalera (
Tito Sotto) - one half of the Escalera brothers, who plots harebrained schemes in every episode. • Josémari "Joey" Escalera (
Joey de Leon) - the other Escalera sibling. Miss Tapia has a crush on him. • Victorio "Vic" Ungasis (
Vic Sotto) - the good-looking and smart
teacher's pet with a "chick magnet" personality. The Escaleras often pick on him during class. Later, he became a professor at Wanbol University. • Liwayway Gawgaw Tapia, a.k.a., Miss Tapia (
Mely Tagasa) - Wanbol University's professor who often gets on the Escalera brothers' nerves. Although she admires Joey Escalera, Miss Tapia was romantically connected with Mang Tem-i. Vic is her favorite student. Miss Tapia was originally a character in the
GMA sitcom
Baltic & Co. (1974-1976), also portrayed by Tagasa.
Baltic & Co. is based on the newspaper
comic strip of the same title created by Roni Santigo.
Baltic & Co. and
Iskul Bukol are unrelated
media franchises. • Artemis Batongbuhay, a.k.a., Mang Tem-i (Bing Angeles) - the dark-complexioned operator of the university's cafeteria. His name is a
vesre on the Filipino word "
itim" (black or dark), "
tim-i" or "
tem-i." • Tonette Macho (Anthony Roquel) - the gay student who plays as best friend of the fairest girl in class (Mary and Joey Anson). He is also the nemesis of the Escalera Brothers. • Aling Jacoba or Inang (
Dely Atay-Atayan) - Vic's mother from the town of Tiaong,
Quezon. Famous for her term of endearment "
bunsooyy!" whenever addressing Vic. The root word "
bunso" is
Tagalog for youngest child. • Sharon Escalera (
Sharon Cuneta) - younger sister of Tito and Joey. • Viviana "Bibeth" Belibet (Bibeth Orteza) - Vic's female roommate and fellow student. • Richie "Kabayo" (
Richie Reyes) - a fellow student who always copies homework from Vic & Bibeth. He is also an accomplice to the Escalera's comedic pranks. • Mary (Mary Massab) - fellow student. • Joey Anson (
Joey Albert) - fellow student. • Kaye Flores (Kaye Torres) - fellow student. • Redford (
Redford White) - Mang Tem-i's houseboy and the cafeteria's waiter. The character was replaced by Jimmy "Big J" (
Jimmy Santos) after the departure of White from the series. • Jimmy "Big J" (
Jimmy Santos) - replacement of Redford at Mang Tem-i's cafeteria. • Perfecto "Pekto" Pangkista (Ariel Villasanta) - a fellow Wanbol student and part-time waiter at Mang Tem-i's canteen who dresses like a 1970s punk rocker. • Don José Escalera (
Rod Navarro) - father of the Escalera siblings. ==Sequels==