•
Agent J (James Darrell Edwards III), a fictional character from
Men in Black •
James Edwards (actor) (1918–1970), American film actor •
James L. Edwards (actor) (born 1972), American actor, screenwriter, and filmmaker •
James Edwards (bookseller) (1757–1816), English bookseller and bibliographer •
James Francis Edwards (1921–2022), Canadian fighter pilot and ace during World War II •
James L. Edwards (academic administrator), president of Anderson University in Indiana •
James R. Edwards (born 1945), American New Testament scholar •
James F. Edwards (1910–1991), American businessman and philanthropist •
James Edwards (character), a fictional character on
One Tree Hill •
Jimmy Edwards (1920–1988), English comedian •
Jimmy Edwards (musician) (1949–2015), British musician •
Jimmie M. Edwards (born 1955), Missouri judge political appointee • James Edwards, American political activist and host of
The Political Cesspool radio program