After graduating, Toynbee spent a short time as Assistant Mistress in Classics at
Cheltenham Ladies' College before being appointed tutor in
classics at
St Hugh's College, Oxford (1921–24). She left there in 1924 in protest at the treatment of
Cecilia Mary Ady, becoming Lecturer in Classics at
Reading University from 1924–27. From 1927 she was Fellow and Director of Studies in Classics at
Newnham College, Cambridge, appointed Lecturer in 1931, where her students included
Lilian Hamilton Jeffery and
Joan Liversidge. In 1951 she became the fourth
Laurence Professor of Classical Archaeology (1951–1962), the only female to hold this prestigious Chair. Toynbee was awarded various research awards and was a student in the 1920s at both the
British School at Athens and the
British School at Rome, maintaining strong links with the latter throughout her career, and serving as the Chair of the Faculty from 1954-59. and dedicated her Thames and Hudson Monograph on 'The Art of the Romans' to Strong in 1965. Her research interests ranged widely, including sculpture, coins and medals, painting, mosaics, gemstones, metalwork and much else. She joined Ward-Perkins and
Kathleen Kenyon on a survey of Roman and Christian remains in
Tripolitania in 1948. In 1949, she is pictured attending the inaugural
Congress of Roman Frontier Studies in Newcastle. In the summer of 1961, Toynbee wrote the handlist and catalogue for a major exhibition at the
Goldsmiths' Hall, London to mark the 50th year of
The Roman Society on the subject of
Roman Art in Britain, She was Vice-President of
The Roman Society from 1946. A review of the Roman Society for its centenary suggests that
Margerie Venables Taylor hoped to have Toynbee appointed President in 1962 but that a trial session of Council made it clear that she was too deaf to function effectively in the post. A complete list of her works to 1972 was published in the Papers of the
British School at Rome. A painting of her by Catriona Jane Cursham held in Newnham College depicts her with a curled up white cat. ==Honours==