Europe De Guzman was discovered by representatives of
Olympique Marseille while playing for the North Scarborough youth soccer club in
Toronto. After playing with Marseille's reserve side, de Guzman became a first-team player with
1. FC Saarbrücken in the
2. Bundesliga in the 2000–01 season, where he made two appearances, and in the 2001–02 season, where he made 19 appearances. In 21 appearances he never scored. In 2002, he joined newly promoted
Hannover 96, becoming only the third Canadian to play in the
Bundesliga. He made 20 appearances during
2002–03 season and 32 appearances in both
2003–04 and
2004–05 seasons. De Guzman's contract with Hannover expired in 2005 allowing him to move to any team with no transfer fee. He was heavily linked with a move to
Tottenham where he would have joined Canadian captain
Paul Stalteri. He decided against the move to London due to the depth in the centre of mid-field, and instead chose to join
Deportivo La Coruña in Spain becoming the first Canadian to play in
La Liga. After playing a starring role in the club's remarkable turnaround in the 2007–2008 season to avoid relegation and gain a spot in the
UEFA Cup, de Guzman was named the team's player of the season. In 95 appearances he scored one goal. His only goal with Deportivo came in 2005 against the Spanish giants
Real Madrid. His contract with Deportivo expired in the summer of 2009.
Toronto FC in 2010 In September 2009 an agreement was reached with
Toronto FC for de Guzman to sign as a
designated player, becoming the first ever Canadian Designated Player in league history. His contract was worth $1,910,746 annually. The Canadian midfielder signed a three-year deal to play in MLS. De Guzman made his debut for the club in an away game against the
Los Angeles Galaxy on September 19, 2009. He finished the
2009 season with five appearances. De Guzman was able to convince former Deportivo teammate and friend
Mista to join Toronto in July 2010. De Guzman was heavily criticized for his inconsistent performances as a designated player in the 2010 season making 36 appearances in all competitions. Much doubt was left over the future of de Guzman and Toronto on November 23 when the club failed to protect him for the
2010 MLS Expansion Draft, meaning
Vancouver Whitecaps FC or
Portland Timbers could select him if they were willing to take on a Designated Players Salary. However, he was untouched going through the sixth round when Vancouver selected
O'Brian White which allowed Toronto to protect one player for the remaining four rounds in which they protected de Guzman . On January 5, 2011, de Guzman revealed that he would be undergoing knee surgery to repair a torn meniscus which might have plagued his performance for the last quarter of the season. In January 2011, Toronto hired
Aron Winter as the head coach of the club to bring in a new style of possession soccer, many pundits believed that this new style would benefit de Guzman's abilities and allow him to succeed within the MLS. Ten days before the new season kicked off it was revealed that de Guzman would miss this first game against Vancouver and potentially a few more, due to Winter not wanting to aggravate the recent successful surgery. De Guzman scored his first goal for Toronto in
CONCACAF Champions League play against
Tauro FC August 18, 2011, the game ended in a 2–0 away victory.
FC Dallas On July 13, 2012, de Guzman was traded to
FC Dallas in exchange for forward
Andrew Wiedeman. De Guzman made his debut for Dallas against
San Jose Earthquakes on July 18, the game ended in a 2–1 away defeat. De Guzman scored his only goal for Dallas on September 15 against
Vancouver, a left footed volley more than 20 yards out six minutes into second half stoppage time. De Guzman remained with FC Dallas through the 2012 season. His contract expired after 2012 and the club made him available for the
2012 MLS Re-Entry Draft in December 2012. de Guzman became a free agent after he went undrafted in both rounds of the draft.
Jahn Regensburg On the last day of the 2012–13 winter transfer window, de Guzman joined
SSV Jahn Regensburg. He made his debut for the team on February 3, playing all 90 minutes in a 1–5 loss against
Hertha BSC. At the end of the season Jahn Regensburg was relegated from
2. Bundesliga, when De Guzman signed in January he had a clause that if they were relegated he would automatically become a free agent. He had made 15 appearances for the club.
Skoda Xanthi Following the
2013 CONCACAF Gold Cup in late July, de Guzman signed for
Skoda Xanthi in the
Super League Greece. His debut came in a third round
UEFA Europa League match against
Standard Liège on August 1. He scored in the second leg of the series on August 8, but Skoda Xanthi would lose 4–2 on aggregate. He made his league debut for the club on August 17 in a 3–0 loss to
PAOK After his contract expired, he looked for a club in or near Germany to be closer to his family, but he has not found anything as of yet.
Ottawa Fury After several months without a club he was rumoured to be signing with
Columbus Crew following a training spell with the MLS club, however a week later de Guzman signed with
Ottawa Fury of the
North American Soccer League on March 27, 2015. He made his debut on April 4 against the
Carolina RailHawks. On December 16, 2015, de Guzman re-signed with Ottawa for the
2016 season. He was subsequently named captain of the club on March 9, 2016.
Gloucester Celtic FC He came out of retirement during the pandemic to play amateur soccer with local side
Gloucester Celtic FC. He helped the team win the 2021 Ontario Cup. ==International career==