Ferré became active in politics in the 1940s. He unsuccessfully ran for mayor of Ponce in 1940 and
Resident Commissioner of Puerto Rico in 1948.
Representative In 1948, Puerto Ricans were allowed to elect their governor; previously the position was filled by appointment by the United States president.
Luis Muñoz Marín was elected governor of Puerto Rico. A movement began which aimed to adopt a
commonwealth relationship with the United States of America. In 1951, a
referendum was held to decide whether to approve or not the option granted by the
United States Congress to draft Puerto Rico's first constitution. Ferré abstained from participating in the process; the pro-statehood party to which he belonged favored the 1951
referendum. He believed that the process would mean "an acceptance of a colony and condemn the people to a perpetual condition of second class citizenship". Ferré later participated in the constitutional assembly created by the
referendum, which drafted the constitution. In 1952 the
Constitution of Puerto Rico was adopted, renaming the body politic of the territory of Puerto Rico as the
Commonwealth of
Puerto Rico. Ferré was elected as a member of the
Constitutional Assembly. That same year Ferré was elected representative in the
Puerto Rico House of Representatives. He ran under the
Republican Statehood Party ("Partido Estadista Republicano") and officially assumed his duties as representative on January 11, 1953.
Governor and Senator event in the 1970s|200x200px On July 23, 1967, a
plebiscite was held to decide if the people of
Puerto Rico desired to become an independent nation, a state of the United States of America, or continue the
commonwealth relation established in 1952. The majority of
Puerto Ricans opted for the
Commonwealth option (see
Puerto Rican status referendums). Disagreement within the then pro-statehood party headed by
Miguel A. García Méndez led Ferré and others to found the
New Progressive Party (a.k.a., PNP). According to declassified documents in 2025, Ferré worked as an asset (codename SKEWER-1) for the CIA during the Cold War. He was tapped in 1957 to help oust the Dominican Republic's Pres. Rafael Trujillo (and to a lesser extent help Cuban exiles after Fidel Castro to power in Cuba). One of the redacted archives state that the U.S. didn't even have to pay Ferre for he was driven by the “suasion of patriotism.” In the following general election in 1968, Ferré ran for
Governor and defeated Luis Negrón López, the candidate of the
Popular Democratic Party (PPD) by a slight margin. The ruling party had split with the creation of the
People's Party, which ran incumbent PDP-elected Governor Roberto Sánchez Vilella as its gubernatorial candidate, ending
Luis Muñoz Marín's PPD's hold on the governor's seat, which had lasted 20 years. During Ferré's administration, Puerto Rico was in an economic boom at 7% GDP growth and the unemployment at 10%. His work as governor of Puerto Rico included defending the federal minimum wage and granting workers a Christmas bonus. He visited
Puerto Rican troops in
Vietnam. In 1970, his first wife, Lorencita, died at La Fortaleza after being bed-ridden for years. Their daughter,
Rosario Ferré, an acclaimed novelist and writer, stepped into the role of
First Lady. During his governorship, he paid special attention to youth affairs and bringing young Puerto Ricans into public service. He successfully had the Puerto Rico Constitution amended to lower the voting age to 18, strongly supported the New Progressive Party Youth organization as party president, appointed then-young statehooders such as
Antonio Quiñones Calderón and
Francisco "Pompi" González to high-level administration jobs, campaigned for a 26-year-old at large House candidate, nominated a future Senate President and Secretary of State, teenager
Kenneth McClintock as Puerto Rico delegate to the 1971
White House Conference on Youth, and strengthened college scholarship programs. Before the Congress created the
United States Environmental Protection Agency in 1971, Ferré had already created Puerto Rico's
Environmental Quality Board in 1970, charged with protecting the islands' environment. In the elections of 1972 he sought reelection but lost to
Rafael Hernández Colón of the PPD. The PPD had claimed that many corruption scandals had been overlooked by the Ferré administration. A bloody student strike at the
University of Puerto Rico at Río Piedras in 1971 had been neutralized by the Puerto Rican police using brute force, something about which Ferré had mixed feelings. Hernández emphasized his youth during the campaign, and became the youngest Puerto Rican governor upon election. All these issues, along with the reunification of the People's Party and the PPD, contributed to a PPD win over Ferré in the election. Ferré remained active in politics and in 1976, he was elected to the
Senate of Puerto Rico. Ferré served as the eighth president of the Senate from 1977 to 1981 and continued serving as senator until 1985. Years after leaving La Fortaleza, he married Tiody De Jesús, a nurse who later became a physician. Ferre attended every
Republican National Convention from
1964 through
1988. This streak ended in 1992 only because Ferre had undergone back surgery the week prior to the
1992 Republican National Convention and could not travel to the convention. After serving as senator, Ferré continued to be active in politics, especially representing the
United States Republican Party on the island. Between 1989 and 1991, Ferré served with former Governor
Carlos Romero Barceló, former representative
Benny Frankie Cerezo, PNP leader
Kenneth McClintock and former congressional staffer
David Gerken as the New Progressive Party's negotiating team while Congress considered Puerto Rico political status legislation introduced by Senator
J. Bennett Johnston. ==Renaissance man==