PR 452 begins in the
Municipality of Brenda-Waskada at an intersection with
PR 251 on the northern end of
Waskada, with the road continuing south into downtown as Park Street. It heads due north out of town as a paved two-lane highway, travelling through farmland and rural areas for several kilometres. After joining
PTH 3 (
Boundary Commission Trail) westbound, the two
run concurrently for before turning north along the border with the
Municipality of Two Borders, bouncing back and forth between asphalt and gravel sections to enter
Napinka at a railway crossing. The highway has an intersection with Railway Avenue, which leads into downtown, before becoming fully paved again as it makes a sharp left turn at an intersection with Dufferin Avenue (former
PR 447 eastbound, leads to
PR 254). Leaving town, PR 452 crosses a bridge over the
Souris River before turning to gravel and heading due west through rural farmland, coming to an end shortly thereafter at an intersection with
PTH 83, just north of
Melita. ==History==