•
Manny Acta (born 1969), Dominican Major League Baseball player, manager and coach •
Manny Alexander (born 1971), Dominican former Major League Baseball player •
Manny Aparicio (born 1995), Canadian soccer player •
Manny Aragon (born 1947), former New Mexico State Senator, later convicted of conspiracy to defraud •
Manny Banuelos (born 1991), Mexican pitcher in Major League Baseball •
Manny Charlton (1941–2022), founding member and lead guitarist of the Scottish hard rock band Nazareth •
Manny Corpas (born 1982), Panamanian pitcher in Major League Baseball and the Mexican Baseball League •
Manny Coto (), Cuban-American film and television writer, director and producer •
Manny Curtis (1911–1984), American songwriter born Emanuel Kurtz •
Manny Delcarmen (born 1982), American pitcher in the Mexican Baseball League •
Manny Diaz (disambiguation), several people •
Manny Elias (born 1953), Indian-born English drummer, original drummer of Tears for Fears •
Manny Fernandez (disambiguation), several people •
Manny González (soccer) (born 1990), Colombian-American soccer player •
Manny Jacinto (born 1987), Filipino-born Canadian actor •
Manny Jones (born 1999), American football player •
Manny Lawson (born 1984), American National Football League player •
Manny Lehman (computer scientist) (1925–2010), German-born British professor of computer science •
Manny Machado (born 1992), Dominican-American Major League Baseball player •
Manny Malhotra (born 1980), Canadian National Hockey League player •
Manny Marroquin (born 1971), Guatemalan-born American mixing engineer •
Manny Martínez (baseball) (born 1970), Dominican Major League Baseball player •
Manny Mota (born 1938), Dominican Major League Baseball player •
Manny Muscat (born 1984), Australian-born Maltese footballer •
Manny Oquendo (1931–2009), American percussionist •
Manny Pacquiao (born 1978), Filipino former boxer and politician •
Manny Paner (born 1949), Philippine Basketball Association player, member of the PBA Hall of Fame •
Manny Parra (born 1982), American Major League Baseball pitcher •
Manny Pérez (born 1969), Dominican-American actor •
Manny Piña (born 1987), Venezuelan baseball player •
Manny Ramirez (born 1972), Dominican-American retired Major League Baseball player •
Manny Ramirez (American football) (born 1983), American National Football League player •
Manny Sanguillén (born 1944), Panamanian Major League Baseball player •
Manny Suárez (born 1993), Chilean-Spanish basketball player •
Manny Trillo (born 1950), Venezuelan Major League Baseball player •
Manny Victorino (born 1959), Philippine Basketball Association player •
Manny Villar (born 1949), Filipino businessman and politician •
Manny Wilkins (born 1995), American football player ==Fictional characters==