On 22 October 1494 Margery married Sir
John Seymour (1476–1536) of
Wulfhall,
Savernake Forest,
Wiltshire. On the same day, her father Henry remarried Lady Elizabeth Scrope. Margery and her husband had ten children together: • John Seymour (died 1510) •
Edward Seymour, 1st Duke of Somerset,
Lord Protector of
Edward VI (c. 1500 – 1552) married, firstly,
Catherine, daughter of Sir William Filliol, and, secondly,
Anne, daughter of Sir Edward Stanhope. •
Sir Henry Seymour (1503–1578) married Barbara, daughter of Morgan Wolfe. •
Thomas Seymour, 1st Baron Seymour of Sudeley (c. 1508 – 1549) married
Katherine Parr, widow of
Henry VIII. • John Seymour (died young) • Anthony Seymour (died c. 1528) •
Jane Seymour (c. 1509 – 1537),
queen consort of Henry VIII and the mother of Edward VI. • Margery Seymour (died c. 1528) •
Elizabeth Seymour (c. 1518 – 1568) married, firstly, Sir
Anthony Ughtred. Married, secondly,
Gregory Cromwell, 1st Baron Cromwell. Her third husband was
John Paulet, 2nd Marquess of Winchester. • Dorothy Seymour married, firstly,
Clement Smith (c. 1515 – 1552) of
Little Baddow, Essex, and, secondly, Thomas Leventhorpe of Shingle Hall,
Hertfordshire. It is presumed that Margery and John had a good relationship in their marriage. After her husband's death, instead of remarrying, she took a larger role in her children's education while running Wulfhall. Notably, her eldest daughter, Jane, was not schooled in a formal setting; Margery instead had her disciplined in more traditional roles that she deemed suitable. Her son Edward, a soldier and royal servant, would become the
Duke of Somerset and Lord Protector. He was the eldest surviving child of the Seymours. File:Edward Seymour.jpg|Edward Seymour, 1st Earl of Hertford, later 1st Duke of Somerset & Lord Protector File:Thomas Seymour Workshop of Holbein.jpg|Portrait Miniature of Thomas Seymour, Workshop of
Hans Holbein the Younger File:Hans Holbein the Younger (workshop of) - Jane Seymour (Mauritshuis).jpg|Jane Seymour, Workshop of Hans Holbein the Younger File:Holbein, Hans (II) - Portrait of a lady, probably of the Cromwell Family formerly known as Catherine Howard - WGA11565.jpg|
Portrait of a Lady, perhaps Elizabeth Seymour, Hans Holbein the Younger ==Death==