Manulis graduated from Columbia in 1935 and began working as an assistant for Ben Boyer, the business manager for producer
Max Gordon, at a salary of $25 a week. Manulis also produced summer stock at Bass Rocks in
Gloucester, Massachusetts, in partnership with
Henry Levin. They invited
John C. Wilson, a producer who was then affiliated with
Noël Coward, to attend one of their productions. Wilson attended the performance and hired Manulis to work in his Broadway office. While employed by Wilson, Manulis directed rehearsals of understudies and reviewed scripts. Also in 1939, he acted in a short-lived Broadway production of
They Walked Alone with
Elsa Lanchester. This was Manulis's last acting performance. He later joked that his character died at the end of Act II, and a critic panned his performance and suggested that the production could be improved if Manulis's character were killed instead at the end of Act I. In June 1940, he was hired as a regular director at the Bass Rocks Theatre in Gloucester. In early 1942, after the United States entered
World War II, Manulis served as a lieutenant in the U.S. Navy and was stationed in
London, England, censoring mail for war sensitive information. By 1950, he had developed a reputation as the "superb manager-director" of the Westport Playhouse. • In September 1946, Manulis directed ''It's a Man's World'' at Westport. • In October 1946, Manulis directed his wife in the lead role in
Made in Heaven! at the
Henry Miller Theatre. • During the summer of 1950, Manulis directed his wife in
The Long Days in the
Theatre Guild's experimental course at Westport. • In November 1950, Manulis was the director of ''Pride's Crossing'', a play starring
Mildred Dunnock and co-starring his wife at Broadway's
Biltmore Theatre. • In January 1951, Manulis produced
Springtime for Henry starring
Edward Everett Horton and Manulis's wife at the winter stock season in the Bahamas. • In January 1952, Manulis co-produced the winter stock season at the Bahama Playhouse at the British Colonial Hotel in Nassau. He directed two of the productions, including
Goodbye Again starring
Tom Ewell and Manulis's wife. ==Television producer==