The origin of the college was in a school for girls opened by
Isabella Thoburn on 18 April 1870 in one room in
Aminabad bazaar of Lucknow. There were then just six girls. By 1871, the school had expanded and moved to occupy a house named Lal Bagh, which had been lived in by the treasurer of the last
Nawab of Awadh. On 12 July 1886 Miss Thoburn's school was renamed as the Lucknow Women's College and began to teach
Fine Arts classes under the supervision of the
University of Calcutta. In 1894, this connection was abandoned in favour of a new one with
Allahabad University. Following the death of Miss Thoburn in 1901, the college, still at Lal Bagh, was given its present name in her honour. In 1923, it moved to the Chand Bagh estate of almost 32 acres, where it has remained until the present day. After its affiliation to Lucknow University it found requisite support and guidance from Nirmal Chandra Chaturvedi, a renowned educationist and member of the university Executive Council. The college's Principal
Sarah Chakko (1905–1954) was the first woman president of the
World Council of Churches. ==Present day==