Western segment (Keene to Bedford) The western terminus of NH 101 is in Keene at the main intersection of NH 9, NH 10, and NH 12 anchoring the South Keene retail district. NH 101 begins eastbound cosigned with southbound NH 10 and NH 12. At a
traffic circle immediately east of this intersection, NH 10 leaves to the south along Winchester Street, while NH 12 turns south at the next major intersection, Main Street. NH 101 continues east through both of these intersections as Marlboro Street, then leaves Keene at the city's southeast corner for the town of
Marlborough. Following Main Street through the
main village of Marlborough, NH 101 meets the western terminus of
NH 124 in the center of the village and then proceeds east into the town of
Dublin. Also known as Main Street in Dublin, NH 101 passes the northern shore of
Dublin Pond and the main offices of
Yankee Publishing (publishers of
Yankee Magazine and the ''
Old Farmer's Almanac'') in the central village of Dublin. There is an intersection with
NH 137 on the eastern side of Dublin, where NH 101 turns southeast. Entering the town of
Peterborough, the road's name changes to Dublin Road, meeting
US 202 in the
main village of Peterborough for a short concurrency along Wilton Road. At Granite Street, where US 202 leaves to the north, another short concurrency begins with
NH 123, which joins NH 101 on Wilton Road. NH 123 leaves southbound on Elm Hill Road, and NH 101 leaves Peterborough at the town's southeastern corner near
Miller State Park and
Pack Monadnock Mountain, a popular hiking and
birdwatching destination. NH 101 next enters the town of
Temple, home to
Temple Mountain, a former ski resort and current state park. Known locally as Gibbons Highway, NH 101 intersects
NH 45 in the northern part of the town and next enters
Wilton. Joining
NH 31 at the northern bank of the
Souhegan River, the two routes cross the river to the south bank before NH 31 leaves to the north in the
main village of Wilton, while NH 101 continues eastward along the south bank of the Souhegan River along Gibbons Highway into neighboring
Milford, where the name changes to Elm Street. West of the
main village of Milford, NH 101 turns southeast onto a
two-lane freeway bypass of the central business district while Elm Street continues on as NH 101A. There is an interchange with
NH 13 and a second interchange with NH 101A as the freeway turns north into
Amherst. The route bypasses to the east of the
Amherst Village Historic District, which covers the
main village of Amherst, and has two interchanges with
NH 122; the southernmost of the two is a half-interchange. Past the northern interchange, the freeway ends and turns northeast.
Bedford and Manchester Entering
Bedford near the town's southwestern corner, the route crosses the town diagonally to the northeast, and at an intersection with
NH 114 turns southeast onto a four-lane divided freeway. Shortly after the beginning of the freeway section is a complex series of interchanges with
US 3 (South River Road), Meetinghouse Road,
I-293 and the
F.E. Everett Turnpike. As NH 101 crosses over the Turnpike, I-293 southbound leaves the Turnpike and joins NH 101 eastbound across the
Merrimack River into the city of
Manchester. In Manchester, there are interchanges with
NH 3A (Brown Avenue) at exit 2 and
NH 28 (South Willow Street) at exit 1, both of which provide access to
Manchester–Boston Regional Airport, the state's largest. The latter exit also provides access to the
Mall of New Hampshire and the large retail district around it. Continuing east, I-293 ends at a Y-interchange with
I-93. NH 101 joins I-93 north for a short concurrency, along which there is a single interchange at exit 6 with Candia Road and Hanover Street. At exit 7, NH 101 leaves I-93 and turns back to the east as a four-lane freeway. The sections of NH 101 that are cosigned with I-93 and I-293 are posted with the mile markers and exit numbers of the respective Interstate, and have a posted speed limit of .
Eastern segment (Manchester to Hampton Beach) After splitting off from I-93, NH 101 is posted with exit numbers beginning sequentially at 1. The westbound exit ramps to I-93 are unnumbered. Between I-93 and exit 1 in Manchester, as well as between I-95 and Landing Road in Hampton, the NH 101 freeway carries a posted speed limit of . The remainder of the freeway has a posted speed limit of and a minimum speed requirement of . in
Candia The NH 101 freeway has one exit in Manchester, exit 1 to
NH 28 Bypass (Londonderry Turnpike), after which NH 101 crosses into
Auburn, north of
Massabesic Lake. In Auburn, exit 2 provides access to Hooksett Road and
NH 121. Next the freeway turns northeast into
Candia, where there is a
trumpet interchange with
NH 43 at exit 3. NH 101 continues southeast, then east into
Raymond, where exit 4 (Old Manchester Road) provides access to the
main village of Raymond and exit 5 provides access to
NH 107 (Freetown Road) with nearby connections to
NH 27,
NH 156 and
NH 102. Continuing east into
Epping, exit 6 serves Depot Road and Beede Hill Road, and exit 7 provides access
NH 125 (Calef Highway). Exit 8 is in Brentwood at North Road, which provides access to the
New England Dragway and NH 27. In Exeter, exits 9 (NH 27) and 10 (
NH 85) each provide access to the
main village and central business district. Exits 11 (
NH 108 to
NH 33 /
NH 88) and exit 12 (
NH 111) are located along the Exeter /
Stratham town line. Entering the seacoast town of
Hampton, NH 101 has an unnumbered and tolled interchange with
I-95 and, immediately afterward, exit 13 connects to NH 27. East of exit 13, NH 101 narrows into a
super-2 freeway. There is an unnumbered interchange with
US 1 (the Hampton
Rotary) which provides access to downtown, before the freeway section ends at a traffic light with Landing Road to the east. NH 101 enters Hampton Beach as a full-access two-lane highway, crosses the marshy estuary system of the
Hampton River and its tributaries, then splits into a pair of one-way streets (Highland Avenue eastbound and Church Street westbound) before reaching its eastern terminus at
NH 1A (Ocean Boulevard). ==History==