Ohio to Warren US 6 enters Pennsylvania from
Ohio in
Crawford County, heading southeast as a two-lane undivided road through farmland and woodland to the north of
Pymatuning State Park, which is home to
Pymatuning Reservoir. The route heads into the borough of
Linesville, where it heads southeast through developed areas of the borough on Penn Street before turning east onto East Erie Street, passing north of
Conneaut Area Senior High School. The road continues southeast through more rural areas as it heads away from the state park, passing over the
Canadian National Railway's
Bessemer Subdivision railroad line. US 6 intersects the southern terminus of
PA 618 before it reaches a junction with
PA 285 on the western edge of the borough of
Conneaut Lake. Here, US 6 heads east for a
concurrency with PA 285 and the two routes head east through the borough on Water Street. The road intersects
US 322/
PA 18 in the center of Conneaut Lake, where the two routes join US 6 and PA 285. A block later, PA 285 splits to the south. US 6/US 322/PA 18 become a five-lane road with a
center left-turn lane and head east out of the borough, passing to the south of
Conneaut Lake. PA 18 splits from US 6/US 322 by turning to the north, with US 6/US 322 continuing east-northeast on Conneaut Lake Road through farms and woods with some development. The road heads into a business area to the west of the city of
Meadville and comes to a
roundabout with
US 19 and the southern terminus of
PA 98, at which point US 19 becomes concurrent with US 6 and US 322. The roadway becomes a four-lane
divided highway and comes to a
cloverleaf interchange with
I-79. Past this interchange, the three routes reach an intersection with the southern terminus of
PA 102 before curving north and entering Meadville upon crossing
French Creek and a
Western New York and Pennsylvania Railroad line. The road becomes French Creek Parkway and US 322 splits to the east, with US 6/US 19 continuing north through developed areas to the east of the railroad line. The two routes leave Meadville and narrow to a two-lane undivided road, passing through wooded areas with some fields and development as it follows the French Creek and the Western New York and Pennsylvania Railroad. In the borough of
Saegertown, US 6/US 19 head north along Main Street and form a concurrency with
PA 198, intersecting PA 198 at roundabouts on either end of the borough. The road continues northeast through more rural areas alongside the creek and railroad, reaching the borough of
Venango. Here, the two routes head north on Church Street before turning east onto Cussewago Street and curving north onto River Street. US 6/US 19 run northeast through farms and woods with some development to the borough of
Cambridge Springs. The two routes head northeast on Venango Avenue before intersecting the northern terminus of
PA 86 and the western terminus of
PA 408 in the center of the borough, where they turn onto North Main Street and continue northeast. US 6/US 19 reach a junction with the southern terminus of
PA 99 before leaving Cambridge Springs and heading through rural areas. US 6/US 19 continue into
Erie County and comes to an intersection with the eastern terminus of
US 6N, at which point US 6 splits from US 19 by turning to the east and crossing French Creek. The route passes through the borough of
Mill Village, where it crosses under a Western New York and Pennsylvania Railroad line, and runs through a mix of farmland and woodland with some development. The road continues through rural land and turns northeast to reach the borough of
Union City, where it comes to a junction with
PA 8. At this point, US 6 heads north along with PA 8 through developed areas of the borough on South Main Street, crossing a Western New York and Pennsylvania Railroad line. In the downtown area of Union City, US 6 splits from PA 8 by turning east onto East High Street at a crossing of a
Buffalo and Pittsburgh Railroad line. The route leaves Union City and heads through farm fields and woods, reaching a junction with
PA 89 to the north of the borough of
Elgin. Here, PA 89 forms a concurrency with US 6 before splitting to the south. The route runs east-northeast through wooded areas with some development prior to entering the city of
Corry. In Corry, US 6 becomes West Columbus Avenue and runs through developed areas in the northern part of the city, crossing
PA 426 and becoming East Columbus Avenue. In the eastern part of Corry, the road passes south of Corry Memorial Hospital. ==History==