Piero took over as leader of Florence in 1492, upon Lorenzo's death. After a brief period of relative calm, the fragile peaceful equilibrium between the Italian states, laboriously constructed by Piero's father, collapsed in 1494 with the decision of King
Charles VIII of France to cross the
Alps with an army in order to assert hereditary claims to the
Kingdom of Naples. Charles had been lured to Italy by
Ludovico Sforza (Ludovico il Moro), ex-regent of
Milan, as a way to eject Ludovico's nephew
Gian Galeazzo Sforza and replace him as duke. After settling matters in Milan, Charles moved towards Naples. He needed to pass through
Tuscany, as well as leave troops there to secure his
lines of communication with Milan. As Charles's army approached Tuscany, he sent envoys to Florence to ask Piero to support his claim to Naples and allow his army to pass through Tuscany. Piero waited five days before responding that Florence would remain neutral. This was unacceptable to Charles, who intended to invade Tuscany, starting with the fortress of
Fivizzano, which he sacked and brutally massacred. Piero attempted to mount a resistance, but received little support from members of the Florentine elite who had fallen under the influence of the fanatical Dominican priest
Girolamo Savonarola. Even his cousins, Lorenzo and Giovanni, allied themselves with Charles, sending him messages to pledge their support and funds. By the end of October, Piero had not succeeded in gaining any support for Florence, and, without consulting the governing
Signoria, decided to visit Charles at his camp and try to win his friendship. During their meeting, Piero acceded to all of Charles's demands, including surrendering the fortresses of
Sarzana,
Pietrasanta,
Sarzanello, and Librafratta, as well as the towns of
Pisa and
Livorno. When Piero returned to Florence to report back to the Signoria, he was greeted with public outrage, and he and his family fled the city for Venice. The family
palazzo was looted, and the substance as well as the form of the
Republic of Florence was re-established with the Medici formally exiled. A member of the Medici family was not to rule Florence again until 1512, when the city was forced to surrender by Giovanni de' Medici, who in 1513 was elected
Pope Leo X, solidifying the family's power. == Exile ==