•
Adam McDonough (born 1985), American mixed martial artist •
Aidan McDonough (born 1999), American ice hockey player •
Al McDonough, Canadian ice hockey player •
Alexa McDonough, Canadian politician •
Ann M. McDonough (1915-1995), member of the Military Intelligence Hall of Fame •
Ann Patrice McDonough, American figure skater •
Arthur Edward McDonogh, (c. 1810 – 1852), New Zealand policeman, police magistrate, militia officer and roading supervisor. •
Brendan McDonough, American soccer player •
Blair McDonough, Australian actor •
Bob McDonogh, American racecar driver •
Brian McDonough, American physician and writer •
Bridget McDonough, American businesswoman •
David McDonough, New York Assemblyman •
Darron McDonough, English footballer •
Declan McDonogh, Irish jockey who competes in Flat racing •
Denis McDonough, US Secretary of Veterans Affairs under President Joe Biden; White House Chief of Staff, Deputy National Security Advisor and National Security Council Chief of Staff under President Barack Obama. •
Eileen McDonough (1962–2012), American child actress •
Elizabeth MacDonough, Parliamentarian of the United States Senate •
Frank McDonough, British historian of 20th-century Germany •
Fred McDonogh, Irish politician •
Gabe McDonough, Canadian record producer who is the vice president music director at Leo Burnett USA •
George Macdonogh, British Army general officer. •
Giles MacDonogh (born 1955), British writer, historian and translator •
Glen MacDonough (1870–1924), US American writer, lyricist and librettist •
Gordon L. McDonough, U.S. Representative from California •
Guy McDonough, Australian rock musician •
Harry Macdonough, Canadian singer and recording executive •
Hubie McDonough, American ice hockey player •
Jack McDonough, Australian rules footballer who played with South Melbourne and Fitzroy in the VFL during the early 1900s •
Jake McDonough, American football defensive end •
James MacDonough (born 1970), American bass guitarist •
James McDonogh, Irish first-class cricketer •
Jenny McDonough, field hockey forward who plays for Ireland •
Jimmy McDonough, American journalist and biographer •
John McDonogh (1779-1850), United States entrepreneur and philanthropist, founder and namesake of McDonoghville Louisiana •
John McDonogh (hurler) (1941–2012), Irish hurler who played as full-back for the Limerick senior team •
John McDonough (piper), Irish piper from County Galway •
John McDonough (Savannah mayor), politician and businessman from Georgia, US •
John McDonough (sports executive) (born 1953), former president of the Chicago Blackhawks ice hockey team •
John E. McDonough (born 1953), professor of public health at the Harvard School of Public Health •
John J. McDonough (Massachusetts politician), American politician who served as a member of the Boston School Committee from 1966 to 1968 and again from 1972 to 1982 •
John J. McDonough (mayor), mayor of St. Paul, Minnesota •
John P. McDonough (politician), American politician from Maryland •
John T. McDonough, Irish born-American lawyer and politician •
Kiki McDonough, British jewellery designer •
Martin McDonogh (1860–1934), Irish politician •
Martin McDonagh, British-Irish playwright and filmmaker •
Marie McDonough (1917–2013), Australian cricketer •
Mary Elizabeth McDonough, American actress • Mary ("Polly") McDonough (1783–1856), mother of
Andrew Johnson, the 17th President of the United States •
Matthew McDonough, drummer for American heavy metal band Mudvayne •
Megon McDonough, American folk/cabaret singer/songwriter •
Neal McDonough, American actor •
Pat McDonough, US Maryland politician •
Patrick MacDonogh (1902–1961), Irish poet •
Patrick McDonough (cyclist) (born 1961), American track cyclist •
Patrick F. McDonough (fl. 1956–2001), Irish-American police officer, attorney, and politician •
Patrick J. McDonough (1911–1980), American politician from Massachusetts •
Paul McDonough (disambiguation), several people •
Pete McDonough, San Francisco bail bondsman •
Peter J. McDonough (1925–1998), American Republican Party politician from New Jersey •
R. C. McDonough (1924–2018), Justice of the Montana Supreme Court •
Roger I. McDonough, American judge, served on the Utah Supreme Court from 1938 to 1966 •
Roy McDonough, English football player and manager who holds the record for red cards in the English professional game •
Ryan McDonough (disambiguation), several people •
Sean McDonough, American television sportscaster •
Sean Daniel (basketball) (born 1989), Israeli basketball player •
Suzanne Clarke McDonough, American journalist, documentary filmmaker •
Thomas Macdonough, 19th-century American naval officer •
Will McDonough, American sportswriter for the
Boston Globe •
William McDonough, American architect and author •
William Joseph McDonough, Federal Reserve Bank of New York chairman ==Given name==