SC 403 was established in 1933 as a renumbering of
US 301 from US 76 in Timmonsville to US 15 at Lees Crossroads. The entire route was paved in 1939. Around 1942, SC 403 was extended south
SC 407 in
Sparrows Crossroads. In 1948, SC 403 was retracted back to its original routing, leaving behind Hill Road (S-21-38). Between 1968 and 1970, SC 403 was extended south to its current southern terminus with SC 341, replacing part of
SC 53 and nearly all of SC 309. Between 2005 and 2012, US 15 was realigned its Lees Crossroads intersection, removing an intersection corner bypass, giving an odd overlap with SC 403 for to where the corner bypass originally reconnected.
South Carolina Highway 309 South Carolina Highway 309 (
SC 309) was an
state highway that was established in 1940 as a new primary routing, from
SC 341 in
Hobbs Crossroads, southeast to
U.S. Route 301 (US 301). By 1942, it was extended southeast to reconnect with SC 341. Between 1968 and 1970, SC 309 was
decommissioned and renumbered as an extension of SC 403 with only its westernmost piece downgraded to secondary road (Lynches River Road; S-42-14). ==Major intersections==