Weil continues to be active in the
Los Angeles theatrical community during hiatuses, is a regular performer at the
Ojai Playwrights Conference in early August and
radio dramas with
L.A. Theatre Works, and still occasionally performs in live theater in
Philadelphia and
New York City. She has acted with every member of her family; in 2004, she headlined with her father in a well-received regional theater production of
Proof at the Montgomery Theater in
Souderton, Pennsylvania, just north of her adopted hometown of
Lansdale. Weil's first television role was in 1994, in an episode of
The Adventures of Pete & Pete called "Yellow Fever". She played a bully; her mother Lisa played a teacher. She also played a second role later in the series as a love interest to Big Pete in the episode "35 Hours". Her younger sister Samantha shared the screen with Liza in the
Gilmore Girls' third-season finale, "Those Are Strings, Pinocchio". Samantha Weil played a student named Bernadette (unrelated to her sister's character Paris) making a video
yearbook entry in front of an impatient Paris, who is standing off to the side waiting to make her own entry. An alumna of
Columbia University, Weil received her first major
feature film role co-starring with
Kevin Bacon in
Stir of Echoes. Before that role, she starred in the 1998
independent film,
Whatever. Her first film was the 1996
short film,
A Cure For Serpents, where she played a daughter of a
mysophobic woman bringing home a boyfriend who was not as obsessive with cleanliness. She also appeared in several other short and feature-length
independent films, such as
Motel Jerusalem,
Scar, and
Lullaby. After her work in
Whatever and
Stir of Echoes,
Warner Bros. signed Weil to a
talent holding deal and she moved to Los Angeles, where she guest-starred on series produced by that studio, including
ER and
The West Wing, before being cast on
Gilmore Girls. Weil was originally considered for the role of
Rory Gilmore by
Gilmore Girls creator
Amy Sherman-Palladino before
Alexis Bledel won the role; the character of Paris Geller was created especially for Weil. She also had a minor role as a
humane society worker in the
Molly Shannon film
Year of the Dog, and appeared as Doris Delay in the 2008 biographical film
Neal Cassady, and as a reporter in the 2010
live-action rotoscoping film
Mars. Weil also voiced a
public service announcement in support of the
American Diabetes Association's
Step Up to Fight Diabetes staircase climb event, which took place in
Center City Philadelphia on October 20, 2007. In 2009, Weil returned to her roots as a regular guest star in various television series, including appearances in
Eleventh Hour,
CSI,
In Plain Sight, ''
Grey's Anatomy, and Private Practice. In February 2010, she began a run as Dr. Glass on the popular Internet series Anyone But Me''; series creator
Susan Miller had officiated at Weil's wedding to
Paul Adelstein in 2006. In March 2011, Weil was cast as Amanda Tanner, a
White House aide, in
ABC's
Scandal, a series written and produced by
Shonda Rhimes. Weil had a recurring role in the series' first season. She is also a frequent collaborator of
independent film director
Noah Buschel, having appeared in most of his work. She co-produced and starred in his 2014 low-budget project
The Situation is Liquid. In February 2014, Weil was cast as Bonnie Winterbottom, an assistant to
Annalise Keating (
Viola Davis) in the ABC series
How to Get Away with Murder, which premiered during the
2014–15 television season. She also reprised her role as Paris Geller in the "Winter" and "Spring" episodes of the
Netflix revival series
Gilmore Girls: A Year in the Life. In 2019, it was revealed that Weil would appear in the third season of the
Amazon Prime Video series
The Marvelous Mrs. Maisel as Carole Keen (a character created in tribute to
bass guitarist Carol Kaye, though Kaye voiced objections to the overall character and portrayal), making that series Weil's third collaboration with the Palladinos. In early 2022, she began a recurring role as FBI agent Katherine Russo in the
Fox series
The Cleaning Lady. ==Personal life==