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Michael Rawlins

Sir Michael David Rawlins was a British clinical pharmacologist and emeritus professor at the University of Newcastle upon Tyne. During his medical career he chaired several executive agencies including the Committee on Safety of Medicines from 1993 to 1998, followed by the National Institute for Health and Care Excellence (NICE) for 14 years from its formation in 1999 and then the Medicines and Healthcare products Regulatory Agency (MHRA) for six years from 2014. From 2012 to 2014 he was president of the Royal Society of Medicine.

Early life and education
Michael Rawlins was born in Shrewsbury, Shropshire on 28 March 1941. His father was the Reverend Jack Rawlins, vicar of Northwood-on-Trent in Staffordshire, and his mother was Evelyn Daphne Douglas-Hamilton who following the death of his father later married a general practitioner. He attended Uppingham School, Rutland, with David Li and left there in 1959. In 1962 he graduated first class from University of London. He obtained his medical degree from St Thomas' Hospital in 1965. == Career ==
Career
Rawlins completed his house jobs in 1967; firstly, in surgery at St Thomas' and then in medicine at Portsmouth. There, one of his early roles was the decision not to approve wide use of Relenza for flu. In 2010, he helped establish the all-party parliamentary group for Huntington's disease in the UK Parliament, supported by more than 40 MPs and peers. From 2012 to 2019 he was chair of UK Biobank. In November 2014 the Medicines and Healthcare Products Regulatory Agency (MHRA) announced the appointment of Rawlins as its new chair, succeeding Gordon Duff. The appointment was renewed for a further three years in 2017. ==Eponymous lectures==
Eponymous lectures
Rawlins delivered several eponymous lectures at the RCP, including the Bradshaw Lecture in 1986. In 1994 he gave the RCP's William Withering lecture. In it, contrary to the widely held belief that digitalis would unlikely pass modern day licensing regulations, he said of Withering's 1785 An account of the foxglove and some of its medical uses ... "Its contents would do justice to an expert report accompanying a Product Licence application to the drug regulatory authority of any state in the European Union". The lecture called for abandoning hierarchy of evidence at a time when Rawlins headed NICE, the UK's main independent agency whose purpose was to assess scientific evidence of medical treatments. The problem with RCTs, he stated, is that they are too generalised. He pointed out that science includes the not so exact but important "judgement". Rawlins quoted William Blake's observation .. "God forbid that truth should be confined to mathematical demonstration", and said in his lecture: The notion that evidence can be reliably placed in hierarchies is illusory. Decision makers need to assess and appraise all the available evidence irrespective of whether it has been derived from randomized controlled trials or observational studies; and the strengths and weaknesses of each need to be understood if reasonable and reliable conclusions are to be drawn. According to philosopher John Worrall, if other physicians in the field of evidence based medicine held similar views to Rawlins, his [Worrall's] own philosophical work on evidence based medicine might not be required. == Honours and awards ==
Honours and awards
Rawlins became a Fellow of the RCP London in 1977, and 10 years later became Fellow of the Royal College of Physicians of Edinburgh. In 2012 he received the Prince Mahidol Award for his contribution to medicine. Zenith Global Health awarded him their Lifetime Achievement Award in 2019. Rawlins was knighted in the 1999 New Year Honours for services to the improvement of patient protection from the side-effects of medicines, and was appointed Knight Grand Cross of the Order of the British Empire (GBE) in the 2017 Birthday Honours for services to the safety of medicines, healthcare, and innovation. ==Personal and family==
Personal and family
In 1963 he married Elizabeth Hambly, a nurse; they divorced in 2005. In 1981 he became the first chairman of the Newcastle upon Tyne SDP and played an active part in the founding and development of the new party. ==Death==
Death
Rawlins died in Darlington from sepsis and heart failure on 1 January 2023, at the age of 81. At the time of his death he was honorary professor at the London School of Hygiene & Tropical Medicine, University of London, and emeritus professor at the University of Newcastle upon Tyne. Rawlins is survived by his daughters Vicky, Lucy, and Suzannah, and eight grandchildren. ==Selected publications==
Selected publications
Articles • • • • Books • • • == References ==
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