Dressler had appeared in two shorts as herself, but her first role in a feature film came in 1914 at the age of 44. In 1902, she had met fellow Canadian
Mack Sennett and helped him get a job in the theater. After Sennett became the owner of his namesake motion picture studio, he convinced Dressler to star in his 1914 silent film ''Tillie's Punctured Romance''. The film was to be the first full-length, six-reel motion picture comedy. According to Sennett, a prospective budget of $200,000 meant that he needed "a star whose name and face meant something to every possible theatre-goer in the United States and the British Empire." The movie was based on Dressler's hit ''Tillie's Nightmare
. She claimed to have cast Charlie Chaplin in the movie as her leading man, and was "proud to have had a part in giving him his first big chance." Instead of his recently invented Tramp character, Chaplin played a villainous rogue. Silent film comedian Mabel Normand also starred in the movie. Tillie's Punctured Romance
was a hit with audiences, and Dressler appeared in two Tillie'' sequels and other comedies until 1918, when she returned to
vaudeville. In 1922, after her husband's death, Dressler and writers Helena Dayton and Louise Barrett tried to sell a script to the Hollywood studios, but were turned down. The one studio to hold a meeting with the group rejected the script, saying all the audiences wanted is "young love". Proposed co-stars such as Lionel Barrymore and
George Arliss were rejected as "old fossils". In 1925, Dressler filmed a pair of two-reel short movies in Europe for producer Harry Reichenbach. The movies, titled the
Travelaffs, were not released and were considered a failure by both Dressler and Reichenbach. Dressler announced her retirement from show business. In early 1927, Dressler received a lifeline from director
Allan Dwan. Although versions differ as to how Dressler and Dwan met, including that Dressler was contemplating suicide, Dwan offered her a part in a film he was planning to make in Florida. The film,
The Joy Girl, an early color production, only provided a small part. Her scenes were finished in two days, so Dressler returned to New York upbeat after her experience with the production. Later that year,
Frances Marion, a screenwriter for the
Metro-Goldwyn-Mayer (MGM) studio, came to Dressler's rescue. Marion had seen Dressler in the 1925 vaudeville tour and witnessed Dressler at her professional low-point. Dressler had shown great kindness to Marion during the filming of
Tillie Wakes Up in 1917, and in return, Marion used her influence with MGM's production chief
Irving Thalberg to return Dressler to the screen. Her first MGM feature was
The Callahans and the Murphys (1927), a rowdy silent comedy co-starring Dressler (as Ma Callahan) with another former Mack Sennett comedian,
Polly Moran, written by Marion. The film was initially a success, but the portrayal of Irish characters caused a protest in the
Irish World newspaper, protests by the American Irish Vigilance Committee, and pickets outside the film's New York theatre. The film was first cut by MGM in an attempt to appease the Irish community, then eventually pulled from release after Cardinal Dougherty of the Archdiocese of Philadelphia called MGM president
Nicholas Schenck. It was not shown again, and the negative and prints may have been destroyed. While the film brought Dressler to Hollywood, it did not re-establish her career. Her next appearance was a minor part in the
First National film
Breakfast at Sunrise. She appeared again with Moran in
Bringing Up Father, another film written by Marion. Dressler returned to MGM in 1928's
The Patsy as the mother of the characters played by stars
Marion Davies and
Jane Winton. Hollywood was converting from silent films, but "
talkies" presented no problems for Dressler, whose rumbling voice could handle both sympathetic scenes and snappy comebacks (the wisecracking stage actress in
Chasing Rainbows and the dubious matron in
Rudy Vallée's
Vagabond Lover). Frances Marion persuaded Thalberg to give Dressler the role of Marthy in the 1930 film
Anna Christie.
Greta Garbo and the critics were impressed by Dressler's acting ability, and so was MGM, which quickly signed her to a $500-per-week contract. Dressler went on to act in comedic films which were popular with movie-goers and a lucrative investment for MGM. She became Hollywood's number-one box-office attraction, and stayed on top until her death in 1934. She also took on serious roles. For
Min and Bill, with
Wallace Beery, she won the 1930–31
Academy Award for Best Actress (the eligibility years were staggered at that time). She was nominated again for Best Actress for her 1932 starring role in
Emma, but lost to
Helen Hayes. Dressler followed these successes with more hits in 1933, including the comedy
Dinner at Eight, in which she received top billing over
John and
Lionel Barrymore,
Jean Harlow,
Billie Burke, and
Wallace Beery. In a magisterial performance, she played an aging but vivacious former stage actress. Dressler had a memorable bit with
Jean Harlow in the film: Harlow: I was reading a book the other day. Dressler: Reading a book? Harlow: Yes, it's all about civilization or something. A nutty kind of a book. Do you know that the guy said that machinery is going to take the place of
every profession? Dressler: Oh my dear, ''that's
something you'' need never worry about. Following the release of
Tugboat Annie Dressler appeared on the cover of
Time magazine in its issue dated August 7, 1933. Despite glamour actresses such as
Greta Garbo,
Joan Crawford, or
Norma Shearer, MGM's most prominent female star at the time was Dressler. The aging star consistently packed movie theaters with hits like
Min and Bill,
Emma, and
Tugboat Annie. An exhibitors' poll in the January 1933 issue of
Motion Picture Herald had Dressler as the number-one box office star in Hollywood. Coming to movie stardom late, Dressler had no pretensions and a delightful sense of humor. Once, when visiting
William Randolph Hearst's California palace San Simeon, a monkey pelted her with some of his excrement. Dressler responded, "Oh, a critic!". Dressler's newly regenerated career came to an abrupt end when she was diagnosed with terminal cancer in the early 1930s. MGM studio head
Louis B. Mayer learned of Dressler's illness from her doctor (who didn't even tell Dressler of her condition). The studio chief took it upon himself to take charge of Dressler's health. To keep her home, he ordered her not to travel, forcing her to miss a charity event in New York. Although furious, Dressler complied. She only learned about her condition six months later. After some experimental cancer therapy, Dressler returned to work under limitations enforced by Mayer. For the rest of her career, the actress only worked three hours a day and had mandatory stand-ins wherever possible. Before she died in July 1934, Dressler starred in three more features, including
Dinner at Eight. She appeared in more than 40 films, and achieved her greatest successes in talking pictures made during the last years of her life. The first of her two autobiographies,
The Life Story of an Ugly Duckling, was published in 1924. A second book,
My Own Story, "as told to Mildred Harrington", appeared a few months after her death. ==Personal life==